Using large-scale respondent driven sampling to monitor the end of an HIV epidemic among persons who inject drugs in Hai Phong, Viet Nam.
Using large-scale respondent driven sampling to monitor the end of an HIV epidemic among persons who inject drugs in Hai Phong, Viet Nam.
复制标题
DOI：
10.1371/journal.pone.0259983
复制
发表时间：
2021
期刊：
影响因子：
3.7
通讯作者：
DRIVE Study Team
中科院分区：
文献类型：
--
作者：
Des Jarlais DC;Arasteh K;Huong DT;Oanh KTH;Feelemyer JP;Khue PM;Giang HT;Thanh NTT;Vinh VH;Le SM;Vallo R;Quillet C;Rapoud D;Michel L;Laureillard D;Moles JP;Nagot N;DRIVE Study Team
描述在中等收入国家使用大规模受访者驱动抽样(RDS)调查来证明在注射吸毒者(PWID)中“艾滋病毒流行的结束”(HIV发病率和0.5/100人年)。需要大样本量才能令人信服地证明发病率非常低。2016-2019年，在越南海防的PWID中进行了4次大型调查(每次约1500 NS)。在招募参与者时，采用了受访者驱动抽样(RDS)，并增加了雪球抽样。HIV发病率是通过新近测试、多次调查的重复参与者以及从调查中招募的PWID的队列研究来衡量的。RDS分析(达到平衡的时间和主要变量的同质性)被用来评估仅RDS与RDS加滚雪球招募的相似/差异。对通过标准RDS招募和滚雪球抽样招募的受访者的特征进行了比较。在增加滚雪球抽样招募时，对RDS对修改的稳健性进行了全面评估。在每次调查的前5周，RDS的招聘效率非常高，每周约有180名受访者参加。招聘随后大幅放缓，在现有的RDS招聘中增加了滚雪球抽样(允许单个受访者招募大量新受访者)。这导致1,383、1,451、1,444和1,268名受访者在13-14周内招聘，接近1,500名受访者/调查的目标。通过标准RDS方法招募的参与者与通过滚雪球方法招募的受访者进行比较，显示出很少的显著差异。RDS分析(快速达到平衡，低亲和性)对每个调查中招募的RDS和参与者总数都是有利的。在越南使用毒品和感染(DRIVE)的方法现已在其他省份正式采用。在增加通过滚雪球抽样招募的少量参与者方面，RDS似乎相当稳健。大样本量可以为中等收入国家中的残疾人群体的政策制定者提供令人信服的证据，证明他们可以“结束艾滋病毒流行”。
To describe the use of large-scale respondent driven sampling (RDS) surveys to demonstrate the “end of an HIV epidemic” (HIV incidence < 0.5/100 person-years) among persons who inject drugs (PWID) in a middle-income country. Large sample sizes are needed to convincingly demonstrate very low incidence rates. 4 large surveys (Ns approximately 1500 each) were conducted among PWID in Hai Phong, Vietnam in 2016–2019. Respondent driven sampling (RDS) with a modification to add snowball sampling was used for recruiting participants. HIV incidence was measured through recency testing, repeat participants across multiple surveys and in a cohort study of PWID recruited from the surveys. RDS analytics (time to equilibria and homophilies for major variables) were used to assess similarities/differences in RDS only versus RDS plus snowball recruiting. Characteristics were compared among respondents recruited through standard RDS recruitment versus through snowball sampling. An overall assessment of the robustness of RDS to modification was made when adding a snowball sampling recruitment. RDS recruiting was very efficient in the first 5 weeks of each survey with approximately 180 respondents recruited per week. Recruiting then slowed considerably, and snowball sampling (permitting an individual respondent to recruit large numbers of new respondents) was added to the existing RDS recruiting. This led to recruiting within 13–14 weeks of 1383, 1451, 1444 and 1268 respondents, close to the target of 1500 respondents/survey. Comparisons of participants recruited through standard RDS method and respondents recruited through snowball methods showed very few significant differences. RDS analytics (quickly reaching equilibria, low homophilies) were favorable for both RDS recruited and total numbers of participants in each survey. DRug use and Infections in ViEtnam (DRIVE) methods have now been officially adopted in other provinces. RDS appears to be quite robust with respect to adding a modest number of participants recruited through snowball sampling. Large sample sizes can provide compelling evidence for “ending an HIV epidemic” to policy makers in a PWID population in a middle income country setting.
登录
查看更多内容
影响因子：
4.4
作者：
Des Jarlais, Don C.;Duong Thi Huong;Nagot, Nicolas
通讯作者：
Nagot, Nicolas
影响因子：
4.2
作者：
Des Jarlais, Don;Pham Minh Khue;Nagot, Nicolas
通讯作者：
Nagot, Nicolas
DOI：
10.1080/00332747.1974.11023794
发表时间：
1974-01-01
影响因子：
2.4
作者：
INGRAHAM, LH
通讯作者：
INGRAHAM, LH
DOI：
10.1097/ede.0b013e31823ac17c
发表时间：
2012-01
期刊：
Epidemiology (Cambridge, Mass.)
影响因子：
--
作者：
McCreesh N;Frost SD;Seeley J;Katongole J;Tarsh MN;Ndunguse R;Jichi F;Lunel NL;Maher D;Johnston LG;Sonnenberg P;Copas AJ;Hayes RJ;White RG
通讯作者：
White RG
影响因子：
1.9
作者：
KAPLAN, CD;KORF, D;STERK, C
通讯作者：
STERK, C