Prevalence of depression, anxiety and post-traumatic stress disorder in health care workers during the COVID-19 pandemic: A systematic review and meta-analysis.

Prevalence of depression, anxiety and post-traumatic stress disorder in health care workers during the COVID-19 pandemic: A systematic review and meta-analysis.
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DOI:
10.1371/journal.pone.0246454
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发表时间:
2021
期刊:
影响因子:
3.7
通讯作者:
Kuper H
Kuper H
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Li Y;Scherer N;Felix L;Kuper H

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COVID-19疫情令医护人员承受心理压力。以前的综述显示,精神障碍在卫生保健工作者中的患病率很高,但这些需要更新和纳入中文研究。本次系统性综述和荟萃分析的目的是提供2019冠状病毒病大流行期间医护人员中抑郁、焦虑和创伤后应激障碍(PTSD)的最新患病率估计值,并受益于纳入的中文发表的研究。系统检索EMBASE、MEDLINE、PsycINFO、Global Health、Web of Science、CINAHL、Google Scholar和中文数据库SinoMed、WanfangMed、CNKI和CQVIP,以检索2019年12月至2020年8月期间进行的关于COVID-19大流行期间医护人员抑郁、焦虑和PTSD患病率的研究。包括以英文和中文发表的研究。关于中度抑郁症、焦虑症和创伤后应激障碍患病率的数据来自65项研究,涉及21个国家的97,333名医护人员。合并的抑郁症患病率为21.7%(95%CI,18.3%-25.2%),焦虑症患病率为22.1%(95%CI,18.2%-26.3%),PTSD患病率为21.5%(95%CI,10.5%-34.9%)。患病率估计还提供了每种疾病的轻度分类。在中东进行的研究中,抑郁和焦虑的合并患病率估计值最高(34.6%; 28.9%)。对协变量进行亚组和荟萃回归分析,包括抽样方法和结局指标。这项系统性综述和荟萃分析发现,在COVID-19大流行期间,医护人员中中度抑郁、焦虑和创伤后应激障碍的患病率很高。迫切需要适当的支持。应对措施将受益于对哪些干预措施能有效减轻这些风险的进一步研究。
The COVID-19 pandemic has placed health care workers under psychological stress. Previous reviews show a high prevalence of mental disorders among health care workers, but these need updating and inclusion of studies written in Chinese. The aim of this systematic review and meta-analysis was to provide updated prevalence estimates for depression, anxiety and post-traumatic stress disorder (PTSD) among health care workers during the COVID-19 pandemic, benefitting from the inclusion of studies published in Chinese. Systematic search of EMBASE, MEDLINE, PsycINFO, Global Health, Web of Science, CINAHL, Google Scholar and the Chinese databases SinoMed, WanfangMed, CNKI and CQVIP, for studies conducted between December 2019 and August 2020 on the prevalence of depression, anxiety and PTSD in health care workers during the COVID-19 pandemic. Studies published in both English and Chinese were included. Data on the prevalence of moderate depression, anxiety and PTSD was pooled across 65 studies involving 97,333 health care workers across 21 countries. The pooled prevalence of depression was 21.7% (95% CI, 18.3%-25.2%), of anxiety 22.1% (95% CI, 18.2%-26.3%), and of PTSD 21.5% (95% CI, 10.5%-34.9%). Prevalence estimates are also provided for a mild classification of each disorder. Pooled prevalence estimates of depression and anxiety were highest in studies conducted in the Middle-East (34.6%; 28.9%). Subgroup and meta-regression analyses were conducted across covariates, including sampling method and outcome measure. This systematic review and meta-analysis has identified a high prevalence of moderate depression, anxiety and PTSD among health care workers during the COVID-19 pandemic. Appropriate support is urgently needed. The response would benefit from additional research on which interventions are effective at mitigating these risks.
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