Properties of rhythmically active reticular neurons around the trigeminal motor nucleus during fictive masticaton in the rat
Properties of rhythmically active reticular neurons around the trigeminal motor nucleus during fictive masticaton in the rat
复制标题
大鼠虚构咀嚼过程中三叉神经运动核周围节律性活跃网状神经元的特性
DOI：
10.1016/0168-0102(92)90072-k
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发表时间：
1992
影响因子：
2.9
通讯作者：
T. Morimoto
中科院分区：
文献类型：
--
作者：
Inoue Tomio;Y. Masuda;T. Nagashima;K. Yoshikawa;T. Morimoto
在麻醉和制动的大鼠上，观察了皮层诱导的虚构咀嚼（CIFM）过程中三叉神经运动核（MoV）周围网状结构神经元的反应特性。43个神经元在CIFM期间有节律性活动（RA神经元），其中大部分位于三叉神经上核和三叉神经脊束核内侧网状结构。在CIFM过程中，36个RA神经元的放电频率以与咬肌或二腹肌神经活动相同的节律被调制。根据激活时相将这些神经元分为4组：16个神经元主要在咬肌活动时相放电（1型），11个在咬肌活动向二腹肌活动的过渡时相放电（2型），5个在二腹肌活动时相放电（3型），4个在二腹肌活动向咬肌活动的过渡时相放电（4型）。43个RA神经元中有39个（91%）对至少一种测试的外周刺激作出反应。反应主要是兴奋性的，但有时也会得到抑制性反应，特别是1型和2型神经元。RA神经元的网状结构内侧的三叉神经脊束核口部的下齿槽神经的刺激，在较短的潜伏期比RA神经元在三叉神经上核。31个RA神经元中有15个（48%）对侧皮层的三脉冲刺激有反应。与此相反，只有5（26%）的19个RA神经元对同侧皮层刺激作出反应。刺激24个RA神经元的同侧MoV，其中9个（A-RA神经元）在0.4- 1.4ms的潜伏期内作出逆向反应，其中8个（89%）接受外周输入。对9个A-RA神经元中的4个应用棘波触发平均法，在所有情况下，在MoV中记录短潜伏期场电位。我们的结论是，三叉神经前运动神经元接受收敛从中央和周边输入。这种整合可以调节咀嚼过程中运动神经元的兴奋性水平。
Response properties of the neurons in the reticular formation around the trigeminal motor nucleus (MoV) were examined during cortically-induced fictive mastication (CIFM) in anesthetized and immobilized rats. Forty-three neurons were rhythmically active (RA neurons) during CIFM, most of which were located in the supratrigeminal nucleus and the reticular formation medial to the oral spinal trigeminal nucleus. The firing frequency of 36 of the RA neurons was modulated in the same rhythm as that of masseteric or digastric nerve activities during CIFM. We divided these neurons into four groups according to the phase of activation: sixteen neurons fired mainly in the phase of masseteric activity (type 1), 11 fired in the transition phase from masseteric activity to digastric activity (type 2), 5 fired in the phase of digastric activity (type 3) and 4 fired in the transition phase from digastric activity to masseteric activity (type 4). Thirty-nine (91%) of the 43 RA neurons responded to at least one of the tested peripheral stimuli. The responses were mostly excitatory but inhibitory responses were sometimes obtained, especially for types-1 and 2 neurons. RA neurons in the reticular formation medial to the oral spinal trigeminal nucleus responded to stimulation of inferior alveolar nerve at a shorter latency than RA neurons in the supratrigeminal nucleus. Fifteen (48%) of 31 RA neurons responded to triple-pulse stimulation of the contralateral cortex. In contrast, only 5 (26%) of the 19 RA neurons responded to the ipsilateral cortical stimulation. Stimulation of the ipsilateral MoV was performed on 24 RA neurons, of which 9 responded antidromically (A-RA neurons) at latencies of 0.4-1.4 ms. Eight (89%) of the 9 A-RA neurons received peripheral inputs. The spike triggered averaging method was applied to 4 of the 9 A-RA neurons, ad in all cases short latency field potentials were recorded in the MoV. We conclude that trigeminal premotor neurons receive convergence from central and peripheral inputs. This integration can adjust the appropriate level of motoneuronal excitability during mastication.
豚鼠皮质诱导的节律性下颌运动期间下颌运动与三叉神经运动神经元膜电位波动之间的关系。
影响因子：
2.5
作者：
Goldberg,LJ;Chandler,SH;Tal,M
通讯作者：
Tal,M