Relationship between tooth loss and mortality in 80-year-old Japanese community-dwelling subjects.
Relationship between tooth loss and mortality in 80-year-old Japanese community-dwelling subjects.
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DOI：
10.1186/1471-2458-10-386
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发表时间：
2010-07-01
影响因子：
4.5
通讯作者：
Takehara T
中科院分区：
文献类型：
--
作者：
Ansai T;Takata Y;Soh I;Awano S;Yoshida A;Sonoki K;Hamasaki T;Torisu T;Sogame A;Shimada N;Takehara T
几项研究的结果表明，牙齿脱落与老年人的健康结果（包括营养不良、生活质量差和死亡率）之间存在关联。然而，在充分考虑了诸如性别和吸烟状况等混杂因素后，关于这些关联在高龄受试者中是否仍然成立的信息有限。在此，我们确定了80岁受试者的牙齿数量是否是死亡率的独立预测因子。我们最初联系了1282名出生于1917年的80岁社区居民，其中697人回应并参与了基线研究，并在4年和5.5年后进行了随访检查。从面谈、医疗和口腔检查中获得数据，并根据口腔内剩余牙齿的数量确定口腔健康状况。在基线研究结束后的4年和5.5年内，分别有108名和157名受试者死亡。在调整了潜在的混杂因素后，牙齿脱落与85.5岁时的死亡率显著相关，但与84岁时的死亡率无关。当分析按性别分层时，我们发现在4岁和5.5岁时进行的随访检查中，女性的相关性更强。另一方面，牙齿脱落对死亡率的影响在吸烟者和非吸烟者之间没有显著差异。牙齿脱落是与健康因素、社会经济地位和生活方式无关的80多岁老人死亡率的重要预测因子，在女性中相关性更强。
Findings from several studies suggest associations between tooth loss and health outcomes, including malnutrition, poor quality of life, and mortality, in older individuals. However, limited information is available regarding whether those associations remain true in very elderly subjects after adequately considering confounding factors such as sex and smoking status. Herein, we determined whether the number of teeth in 80-year-old subjects is an independent predictor of mortality. We initially contacted 1282 80-year-old community-dwelling individuals born in 1917, of whom 697 responded and participated in a baseline study, with follow-up examinations conducted 4 and 5.5 years later. Data from interviews and medical and oral examinations were obtained, and oral health was determined according to the number of teeth remaining in the oral cavity. A total of 108 and 157 subjects died in 4 years and 5.5 years, respectively, after the baseline study. Tooth loss was significantly associated with mortality at age 85.5, but not at age 84, after adjusting for potential confounders. When the analysis was stratified by sex, we found a stronger association in females in follow-up examinations conducted at both 4- and 5.5 years. On the other hand, the effect of tooth loss on mortality was not significantly different between smokers and non-smokers. Tooth loss is a significant predictor of mortality independent of health factors, socio-economic status, and lifestyle in octogenarians, with a stronger association in females.
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影响因子：
2
作者：
Morita, Ichizo;Nakagaki, Haruo;Sheiham, Aubrey
通讯作者：
Sheiham, Aubrey
影响因子：
37.8
作者：
Janket, SJ;Qvarnström, M;Jones, JA
通讯作者：
Jones, JA
影响因子：
3.2
作者：
Sheiham, A;Steele, J
通讯作者：
Steele, J
影响因子：
6.7
作者：
Montebugnoli, L;Servidio, D;Melloni, C
通讯作者：
Melloni, C
影响因子：
1.9
作者：
Hämäläinen, P;Meurman, JH;Heikkinen, E
通讯作者：
Heikkinen, E