Wnt signaling in triple-negative breast cancer.
Wnt signaling in triple-negative breast cancer.
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Wnt信号在三阴性乳腺癌中的作用
DOI：
10.1038/oncsis.2017.14
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发表时间：
2017-04-03
期刊：
影响因子：
6.2
通讯作者：
Dharmarajan A
中科院分区：
文献类型：
--
作者：
Pohl SG;Brook N;Agostino M;Arfuso F;Kumar AP;Dharmarajan A
Wnt signaling regulates a variety of cellular processes, including cell fate, differentiation, proliferation and stem cell pluripotency. Aberrant Wnt signaling is a hallmark of many cancers. An aggressive subtype of breast cancer, known as triple-negative breast cancer (TNBC), demonstrates dysregulation in canonical and non-canonical Wnt signaling. In this review, we summarize regulators of canonical and non-canonical Wnt signaling, as well as Wnt signaling dysfunction that mediates the progression of TNBC. We review the complex molecular nature of TNBC and the emerging therapies that are currently under investigation for the treatment of this disease.
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影响因子：
3.7
作者：
Castiglia, Danielle;Bernardini, Silvia;D'Atri, Stefania
通讯作者：
D'Atri, Stefania
影响因子：
3.8
作者：
Avery-Kiejda KA;Braye SG;Mathe A;Forbes JF;Scott RJ
通讯作者：
Scott RJ
影响因子：
8
作者：
Botlagunta, M.;Vesuna, F.;Raman, V.
通讯作者：
Raman, V.
影响因子：
64.8
作者：
通讯作者：
--
乳腺癌中毛躁6（FZD6）基因组扩增的功能和预后意义。
DOI：
10.1002/path.4841
发表时间：
2017-02
期刊：
The Journal of pathology
影响因子：
--
作者：
Corda G;Sala G;Lattanzio R;Iezzi M;Sallese M;Fragassi G;Lamolinara A;Mirza H;Barcaroli D;Ermler S;Silva E;Yasaei H;Newbold RF;Vagnarelli P;Mottolese M;Natali PG;Perracchio L;Quist J;Grigoriadis A;Marra P;Tutt AN;Piantelli M;Iacobelli S;De Laurenzi V;Sala A
通讯作者：
Sala A