Experience-dependent slow-wave sleep development
Experience-dependent slow-wave sleep development
复制标题
经验依赖的慢波睡眠发展
DOI：
10.1038/nn1064
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发表时间：
2003
影响因子：
25
通讯作者：
T. Hensch
中科院分区：
文献类型：
--
作者：
H. Miyamoto;H. Katagiri;T. Hensch
睡眠增强新皮质的可塑性，从而改善感觉学习。在这里，我们表明，猫和小鼠的睡眠本身会因关键时期后期的清醒经历而发生变化。黑暗饲养导致睡眠期间慢波电活动强烈且可逆的减少，这种减少仅限于视觉皮层，并因 NMDA 受体功能的基因靶向减少而受损。
Sleep enhances plasticity in neocortex, and thereby improves sensory learning. Here we show that sleep itself undergoes changes as a consequence of waking experience during a late critical period in cats and mice. Dark-rearing produced a robust and reversible decrement of slow-wave electrical activity during sleep that was restricted to visual cortex and impaired by gene-targeted reduction of NMDA receptor function.
影响因子：
56.9
作者：
Crair, MC;Gillespie, DC;Stryker, MP
通讯作者：
Stryker, MP