Genetic hitch-hiking in a subdivided population.
Genetic hitch-hiking in a subdivided population.
复制标题
细分人群中的遗传搭便车。
DOI：
10.1017/s001667239800319x
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发表时间：
1998
期刊：
影响因子：
--
通讯作者：
Wiehe,T
中科院分区：
文献类型：
--
作者：
Slatkin,M;Wiehe,T
在假定种群间迁移率相对于新产生的有利等位基因的选择系数较小的情况下，分析了地理细分群体中的遗传搭便车问题。当每代移民数（Nm）小于1时，本文所采用的近似方法是有效的。近似分析表明，搭便车可以导致种群间与优势等位基因密切相关的中性等位基因频率的显著差异。因此，在遗传搭便车被认为是导致基因组中有限杂交区域的低水平遗传变异性的情况下，通过在基因组的相同区域中发现不寻常的地理分化模式，可能会找到证实这一假设的证据。
The problem of genetic hitch-hiking in a geographically subdivided population is analysed under the assumption that migration rates among populations are relatively small compared with the selection coefficient for a newly arising advantageous allele. The approximate method used in the paper is valid when the number of emigrants per generation (Nm) is less than one. The approximate analysis shows that hitch-hiking can result in substantial differences among populations in the frequencies of neutral alleles closely linked to the advantageous allele. Thus, in cases for which genetic hitch-hiking is thought to be responsible for low levels of genetic variability in regions of the genome with restricted crossing over, it might be possible to find confirmatory evidence for that hypothesis by finding unusual patterns of geographic differentiation in the same regions of the genome.
遗传重组和群体细分对果蝇核苷酸序列变异的影响
DOI：
--
发表时间：
1994
期刊：
影响因子：
--
作者：
W. Stephan
通讯作者：
W. Stephan
影响因子：
1.4
作者：
STEPHAN, W;WIEHE, THE;LENZ, MW
通讯作者：
LENZ, MW