Effects of Genetic Recombination and Population Subdivision on Nucleotide Sequence Variation in Drosophila ananassae
Effects of Genetic Recombination and Population Subdivision on Nucleotide Sequence Variation in Drosophila ananassae
复制标题
遗传重组和群体细分对果蝇核苷酸序列变异的影响
DOI:
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发表时间:
1994
期刊:
影响因子:
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通讯作者:
W. Stephan
中科院分区:
文献类型:
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作者:
W. Stephan
Genetic variation in regions of high and low recombination rates was quantified at the DNA sequence level for two natural Drosophila ananassae populations from Myanmar and India. Gene flow between these populations is limited. Levels of DNA sequence variation in regions of low crossing-over per physical length are significantly lower than in regions of intermediate to high crossing-over. Furthermore fixed between-population differences were found in low crossing-over regions but not in regions of high crossing-over. In the latter ones frequency shifts in polymorphisms between populations are more gradual. Simple models of directional selection in conjunction with hitchhiking explain these observations only partially. Local adaptive sweeps have to be postulated to account for the rapid genetic differentiation in regions of restricted recombination.
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