UTR-Dependent Control of Gene Expression in Plants.

UTR-Dependent Control of Gene Expression in Plants.
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DOI:
10.1016/j.tplants.2017.11.003
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发表时间:
2018-03
影响因子:
20.5
通讯作者:
Zhu JK
Zhu JK
中科院分区:
生物学1区
文献类型:
--
作者:
Srivastava AK;Lu Y;Zinta G;Lang Z;Zhu JK

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在植物的一生中,植物感受到许多发育和环境刺激,并且针对这些刺激的最佳反应的激活需要广泛的转录重编程。为了促进这种激活,植物mRNA含有“UTR”或非翻译区,其通过从同一基因产生多个mRNA变体来显著增加基因组的编码能力。在这篇综述中,我们比较了拟南芥(拟南芥)和水稻(Oryza sativum)在基因组水平上的UTR,以突出其在作物中的复杂性。我们讨论了不同模式的UTR为基础的调控,重点是基因,调节多个植物过程,包括开花,胁迫反应,和营养平衡。我们证明了可变UTR长度基因的功能特异性,并提出了未来的研究方向。
Throughout their lives, plants sense many developmental and environmental stimuli, and activation of optimal responses against these stimuli requires extensive transcriptional reprogramming. To facilitate this activation, plant mRNA contains “UTRs” or untranslated regions that significantly increase the coding capacity of the genome by producing multiple mRNA variants from the same gene. In this review we compare UTRs of arabidopsis (Arabidopsis thaliana) and rice (Oryza sativum) at genome scale to highlight their complexity in crop plants. We discuss different modes of UTR-based regulation with emphasis on genes that regulate multiple plant processes, including flowering, stress responses, and nutrient homeostasis. We demonstrate functional specificity in genes with variable UTR length and propose future research directions.
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