Judging semantic similarity: an event-related fMRI study with auditory word stimuli.
Judging semantic similarity: an event-related fMRI study with auditory word stimuli.
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DOI：
10.1016/j.neuroscience.2010.04.029
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发表时间：
2010-08-11
期刊：
影响因子：
3.3
通讯作者：
Caramazza, A.
中科院分区：
文献类型：
--
作者：
Mahon, B. Z.;Caramazza, A.
精神生活的大部分内容是思考目前不在知觉范围内的客体概念。能够维持和比较多种表征的一般系统被称为“工作记忆”，涉及内侧和外侧顶叶和额叶皮层的区域（例如）。人们一直认为，工作记忆的内容索引了大脑中对处理和存储客体知识至关重要的区域的信息。为了研究共同对象概念的思考过程，我们使用事件相关功能磁共振成像（event - related fMRI）来研究参与者在对顺序呈现的听觉单词对概念相似性进行判断时的BOLD活动。通过传统的功能磁共振成像分析方法和多体素模式分析（MVPA）的结合，我们发现与一对单词中的第二个单词相关的大脑反应携带了这对单词中两个成员之间概念相似性的信息。在这两种分析方法中，涉及工作记忆和决策部分的额叶和顶叶区域就是这种情况。然而，在大脑的其他区域，包括早期视觉区域，MVPA允许对语义距离关系进行分类，而传统的平均方法无法显示差异。这些发现表明，在某些区域，漫漫性和统计上低于阈值的BOLD活动“散射”可能携带有关心理表征内容的大量信息。
Much of mental life consists in thinking about object concepts that are not currently within the scope of perception. The general system that enables multiple representations to be maintained and compared is referred to as ‘working memory’, and involves regions in medial and lateral parietal and frontal cortex (e.g.,). It has been assumed that the contents of working memory index information in regions of the brain that are critical for processing and storing object knowledge. To study the processes involved in thinking about common object concepts, we used event related fMRI to study BOLD activity while participants made judgments of conceptual similarity over pairs of sequentially presented auditory words. Through a combination of conventional fMRI analysis approaches and multi-voxel pattern analysis (MVPA), we show that the brain responses associated with the second word in a pair carry information about the conceptual similarity between the two members of the pair. This was the case in frontal and parietal regions involved in the working memory and decision components of the task for both analysis approaches. However, in other regions of the brain, including early visual regions, MVPA permitted classification of semantic distance relationships where conventional averaging approaches failed to show a difference. These findings suggest that diffuse and statistically sub-threshold ‘scattering’ of BOLD activity in some regions may carry substantial information about the contents of mental representations.
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影响因子：
--
作者：
Pelli, DG
通讯作者：
Pelli, DG
影响因子：
25
作者：
Turken, AU;Swick, D
通讯作者：
Swick, D
影响因子：
16.2
作者：
Spiridon, M;Kanwisher, N
通讯作者：
Kanwisher, N
DOI：
10.1016/s0022-5371(73)80056-8
发表时间：
1973-01-01
期刊：
JOURNAL OF VERBAL LEARNING AND VERBAL BEHAVIOR
影响因子：
--
作者：
RIPS, LJ;SHOBEN, EJ;SMITH, EE
通讯作者：
SMITH, EE
影响因子：
25
作者：
Kriegeskorte, Nikolaus;Simmons, W. Kyle;Bellgowan, Patrick S. F.;Baker, Chris I.
通讯作者：
Baker, Chris I.