Platelet function in patients with diabetes mellitus: from a theoretical to a practical perspective.
Platelet function in patients with diabetes mellitus: from a theoretical to a practical perspective.
复制标题
DOI:
10.1155/2011/742719
复制
发表时间:
2011
影响因子:
2.8
通讯作者:
Resar JR
中科院分区:
文献类型:
--
作者:
Kakouros N;Rade JJ;Kourliouros A;Resar JR
Patients with diabetes mellitus have an increased prevalence of vascular disease. Pathologic thrombosis associated with atherosclerotic plaque rupture is a major cause of morbidity and mortality. Platelets are intimately involved in the initiation and propagation of thrombosis. Evidence suggests that platelets from patients with type 2 diabetes have increased reactivity and baseline activation compared to healthy controls. We review the pathophysiology of platelet hyperreactivity in DM patients and its implications in clinical practice, with particular focus on acute coronary syndromes, percutaneous coronary intervention, and novel antiplatelet agents.
登录
查看更多内容
影响因子:
120.7
作者:
Breet, Nicoline J.;van Werkum, Jochem W.;ten Berg, Jurrien M.
通讯作者:
ten Berg, Jurrien M.
影响因子:
120.7
作者:
Becker, DM;Segal, J;Faraday, N
通讯作者:
Faraday, N
影响因子:
37.8
作者:
Calkin, Anna C.;Drew, Brian G.;Jackson, Shaun P.
通讯作者:
Jackson, Shaun P.
影响因子:
39.3
作者:
Angiolillo, Dominick J.;Capranzano, Piera;Bass, Theodore A.
通讯作者:
Bass, Theodore A.
影响因子:
2.8
作者:
Beigel, Roy;Hod, Hanoch;Matetzky, Shlomi
通讯作者:
Matetzky, Shlomi