Intra- and interscan reproducibility using Fourier Analysis of STimulated Echoes (FAST) for the rapid and robust quantification of left ventricular twist.
Intra- and interscan reproducibility using Fourier Analysis of STimulated Echoes (FAST) for the rapid and robust quantification of left ventricular twist.
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DOI：
10.1002/jmri.24162
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发表时间：
2014-02
影响因子：
4.4
通讯作者：
Ennis, Daniel B.
中科院分区：
文献类型：
--
作者：
Reyhan, Meral;Kim, Hyun J.;Brown, Matthew S.;Ennis, Daniel B.
评估使用FAST的左心室扭转的扫描内和扫描间再现性。评估新的磁共振成像（MRI）生物标志物测量的重现性是验证的重要组成部分。STIMulated Echoes的傅立叶分析（FAST）是一种新的MRI组织标记方法，最近已被证明可以与心脏标记图像的左心室（LV）扭曲的传统估计进行比较，但显著减少了用户交互时间。健康志愿者（N=10）在一周内使用FAST扫描两次。在第-1天，收集两次LV扭转测量值，用于扫描内比较。在第8天再次收集LV扭转的测量值，用于扫描间评估。在3 T扫描仪上采集LV短轴标记图像，以确保标记在早期和中期的可检测性。峰值LV扭转报告为平均值±SD。使用一致性相关系数（CCC）和重复性系数（RC）（95%-CI范围）评估重现性。平均峰值扭转测量值为13.4±4.3°（第-1天，扫描-1）、13.6±3.7°（第-1天，扫描-2）和13.0±2.7°（第-8天）。Bland-Altman分析得出的扫描内和扫描间偏倚和95%-CI分别为−0.6° [−1.0°，1.6°]和1.4° [−1.0°，3.0°]。对于扫描内和扫描间，峰值LV扭转的Bland-Altman RC分别为2.6°和4.0°。对于扫描内和扫描间的峰值LV扭转，CCC分别为0.9和0.6。FAST是一种半自动化方法，可快速定量评估LV收缩期和舒张期扭转，在初步研究中显示出较高的扫描内和中等的扫描间重现性。
To assess the intra- and inter-scan reproducibility of LV twist using FAST. Assessing the reproducibility of the measurement of new magnetic resonance imaging (MRI) biomarkers is an important part of validation. Fourier Analysis of STimulated Echoes (FAST) is a new MRI tissue tagging method that has recently been shown to compare favorably to conventional estimates of left ventricular (LV) twist from cardiac tagged images, but with significantly reduced user interaction time. Healthy volunteers (N=10) were scanned twice using FAST over one week. On Day-1 two measurements of LV twist were collected for intra-scan comparisons. Measurements for LV twist were again collected on Day-8 for inter-scan assessment. LV short-axis tagged images were acquired on a 3T scanner in order to ensure detectability of tags during early and mid-diastole. Peak LV twist is reported as mean±SD. Reproducibility was assessed using the concordance correlation coefficient (CCC) and the repeatability coefficient (RC) (95%-CI range). Mean peak twist measurements were 13.4±4.3° (Day-1, Scan-1), 13.6±3.7° (Day-1, Scan-2), and 13.0±2.7° (Day-8). Bland-Altman analysis resulted in intra- and inter-scan bias and 95%-CI of −0.6° [−1.0°, 1.6°] and 1.4° [−1.0°, 3.0°], respectively. The Bland-Altman RC for peak LV twist was 2.6° and 4.0° for intra- and inter-scan respectively. The CCC was 0.9 and 0.6 for peak LV twist for intra- and inter-scan respectively. FAST is a semi-automated method that provides a quick and quantitative assessment of LV systolic and diastolic twist that demonstrates high intra-scan and moderate inter-scan reproducibility in preliminary studies.
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DOI：
10.1186/1532-429x-14-49
发表时间：
2012-07-24
期刊：
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
影响因子：
--
作者：
Young AA;Cowan BR
通讯作者：
Cowan BR
影响因子：
14
作者：
Sengupta, Partho P.;Tajik, A. Jamil;Khandheria, Bijoy K.
通讯作者：
Khandheria, Bijoy K.
影响因子：
3.3
作者：
Cheung, Yiu-fai;Wong, Sophia J.;Cheung, Eddie W. Y.
通讯作者：
Cheung, Eddie W. Y.
影响因子：
19.7
作者：
AXEL, L;DOUGHERTY, L
通讯作者：
DOUGHERTY, L
影响因子：
6.4
作者：
Russel, Iris K.;Tecelao, Sandra R.;Marcus, J. Tim
通讯作者：
Marcus, J. Tim