Dietary phosphorus intake and distribution in Chinese peritoneal dialysis patients with and without hyperphosphatemia
Dietary phosphorus intake and distribution in Chinese peritoneal dialysis patients with and without hyperphosphatemia
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中国腹膜透析患者伴或不伴高磷血症的膳食磷摄入量和分布
DOI：
10.1007/s10157-014-1024-8
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发表时间：
2015-08
影响因子：
2.3
通讯作者：
Qian, Jiaqi
中科院分区：
文献类型：
--
作者：
Yuan, Jiangzi;Lin, Aiwu;Ni, Zhaohui;Qian, Jiaqi
本研究旨在分析腹膜透析(PD)患者膳食磷的摄入量及其在不同食物中的分布，探讨膳食磷摄入量与高磷酸盐血症的关系。使用食物组成计算机程序计算膳食磷和其他营养素含量。结果93例PD患者[年龄52.9±13.0岁，PD持续时间30.1(8.0，71.0)个月]完成了为期3天的饮食日记。高磷血症患者(血磷1.97±0.28 mm ol/L，n=48)的膳食磷摄入量(771.6±0.28)mg/d比620.8±155.3 mm o l/d(p=0.040)明显高于血磷正常者(1.37±0.21 mm o l/L，n=945)，其原因是肉类、零食、饮料、调味品和添加剂的磷摄入量较高。将血磷维持在正常范围的无尿症患者膳食磷摄入量(605.6±122.5)mg/d和磷/蛋白比值(12.7±111.4)mg/g显著降低。多元线性回归分析显示，正常磷摄入量、肾脏CPH和膳食蛋白质摄入量与血磷水平独立相关。结论PD患者膳食磷摄入量过高与血磷水平升高有关。研究建议帕金森病患者，特别是无尿患者，应限制肉类、零食、饮料、食品调味品和添加剂的摄入量，以减少饮食中的磷摄入量。
BackgroundThe present study was conducted to analyze the dietary phosphorus intake and distribution in different food categories in peritoneal dialysis (PD) patients, to evaluate the relationship between dietary phosphorus intake and hyperphosphatemia.MethodsIt was a cross-sectional study, in which prevalent Chinese PD patients were instructed by dietitians to record 3-day diet diary. Dietary phosphorus and other nutrient contents were calculated using a food composition computer program. Renal and peritoneal phosphorus clearance (CPh) was estimated, and serum phosphorus, as well as other serological parameters, were measured at the same time.Results93 PD patients [age 52.9 ± 13.0 years, PD duration 30.1 (8.0, 71.0) months] finished the 3-day diet diary. Hyperphosphatemic patients (serum phosphorus level 1.97 ± 0.28 mmol/l,n= 48) showed higher dietary phosphorus intake (771.6 ± 195.1 versus 620.8 ± 155.3 mg/day,p= 0.040) than those with normal serum phosphorus level (1.37 ± 0.21 mmol/l,n= 45), due to greater phosphorus intake from meat, snacks, beverage, food condiments and additives. Significantly lower dietary phosphorus intake (605.6 ± 122.5 mg/day) and phosphorus to protein ratio (12.7 ± 1.4 mg/g) were observed in patients with anuria who maintained serum phosphorus within normal range. Multivariate linear regression analysis indicated normalized phosphorus intake, renal CPh and dietary protein intake were independently associated with serum phosphorus level.ConclusionHigh dietary phosphorus intake is associated with elevated serum phosphorus level in PD patients. The study suggests that PD patients, particularly those with anuria, shall limit the intake of meat, snacks, beverage, food condiments and additives to reduce dietary phosphorus ingestion.
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DOI：
10.2215/cjn.03950609
发表时间：
2009-08
期刊：
Clinical journal of the American Society of Nephrology : CJASN
影响因子：
--
作者：
J. Uribarri
通讯作者：
J. Uribarri
影响因子：
13.2
作者：
Noordzij, M;Korevaar, JC;Krediet, RT
通讯作者：
Krediet, RT
DOI：
10.1053/ajkd.2001.24542
发表时间：
2001-06
期刊：
American journal of kidney diseases : the official journal of the National Kidney Foundation
影响因子：
--
作者：
J. Uribarri
通讯作者：
J. Uribarri
影响因子：
19.6
作者：
RAMIREZ, JA;EMMETT, M;FORDTRAN, JS
通讯作者：
FORDTRAN, JS
DOI：
10.1016/s1051-2276(99)90019-5
发表时间：
1999
期刊：
Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation
影响因子：
--
作者：
Anne M. Griffiths;Lesley Russell;Marion Breslin;Gavin Russell;Sheryl M. Davies
通讯作者：
Anne M. Griffiths;Lesley Russell;Marion Breslin;Gavin Russell;Sheryl M. Davies