Linguistic and psychometric validation of the MSSS-88 questionnaire for patients with multiple sclerosis and spasticity in Germany.
Linguistic and psychometric validation of the MSSS-88 questionnaire for patients with multiple sclerosis and spasticity in Germany.
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DOI：
10.1186/s12955-014-0119-y
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发表时间：
2014-08-01
影响因子：
3.6
通讯作者：
Flachenecker P
中科院分区：
文献类型：
--
作者：
Henze T;von Mackensen S;Lehrieder G;Zettl UK;Pfiffner C;Flachenecker P
多发性硬化症（MS）是一种炎症性疾病，其中许多患者患有痉挛，影响他们的生活质量。本文的目的是语言验证和心理测量测试多发性硬化症痉挛量表（MSSS-88）在德语MS患者。研究分为两个阶段：1）将原始MSSS-88量表向前/向后翻译成德语，与MS专家进行讨论，并与MS患者进行认知汇报; 2）对德语版本进行心理测量评估。数据收集参加了德国的一项观察性多中心研究（MOVE 2）。与三位MS专家讨论了MSSS-88量表的德语翻译;随后与12名MS患者进行了两次认知情况报告会。对于心理测量评估，87名平均年龄为50.2 ± 10.4岁的MS患者填写了MSSS-88;其中26.4%有严重痉挛。数据质量可接受。MSSS-88项目的缺失数据较低（范围0-5.75%）。MSSS-88的心理测量学测试显示了良好的信度和效度。MS痉挛和睡眠障碍的严重程度，分级，类型和自我评级组之间的显着差异被发现。MSSS-88的变化的敏感性，可以证明与大麻素oromuclidine喷雾剂治疗的MS患者组与非治疗的患者。在治疗组中，发现“肌肉痉挛”、“情绪健康”和“疼痛/不适”发生了中度效应量的显著变化。未给药组未检测到显著变化。这项小型研究的初步证据支持MSSS-88德语版测量MS痉挛影响的可靠性、有效性和反应性。
Multiple sclerosis (MS) is an inflammatory disease where many of the patients suffer from spasticity impacting their quality-of-life. The purpose of this paper was to linguistically validate and psychometrically test the Multiple Sclerosis Spasticity Scale (MSSS-88) in German speaking MS patients. The study had two stages: 1) forward/backward translations of the original MSSS-88 scale into German, discussions with MS-experts and cognitive debriefings with MS patients; 2) psychometric evaluation of the German version. Data collection took part in an observational multi-centre study in Germany (MOVE2). The German translation of the MSSS-88 scale was discussed with three MS-experts; followed by two cognitive debriefing sessions with 12 MS patients. For psychometric evaluation the MSSS-88 was filled in by 87 MS patients with a mean age of 50.2 ± 10.4 years; 26.4% of them had severe spasticity. Data quality was acceptable. Missing data for items of the MSSS-88 were low (range 0–5.75%). Psychometric testing of the MSSS-88 revealed excellent values for reliability and validity. Significant differences between groups regarding severity, grading, type and self-ratings of MS-spasticity and sleep disturbances were found. Sensitivity to change could be demonstrated for the MSSS-88 in the group of MS patients treated with cannabinoid oromucosal spray vs. non-treated patients. In the treated group significant changes with a moderate effect size were found for ‘muscle spasms’, ‘emotional health’ and ‘pain/discomfort’. No significant changes could be detected in the non-treated group. Preliminary evidence from this small study supports reliability, validity, and responsiveness of the German version of the MSSS-88 for measuring the impact of spasticity in MS.
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影响因子：
2.3
作者：
Arroyo, Rafael;Vila, Carlos;Clissold, Steve
通讯作者：
Clissold, Steve
DOI：
10.1177/1352458507082480
发表时间：
2008-03-01
期刊：
MULTIPLE SCLEROSIS
影响因子：
--
作者：
Flachenecker, Peter;Meissner, Heike
通讯作者：
Meissner, Heike
影响因子：
7.2
作者：
GUILLEMIN, F;BOMBARDIER, C;BEATON, D
通讯作者：
BEATON, D
影响因子：
6
作者：
Healy, Brian;Chitnis, Tanuja;Engler, David
通讯作者：
Engler, David
影响因子：
14.5
作者：
Hobart, JC;Riazi, A;Zajicek, JP
通讯作者：
Zajicek, JP