Mechanistic models of microbial community metabolism.
Mechanistic models of microbial community metabolism.
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DOI:
10.1039/d0mo00154f
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发表时间:
2021-06-14
期刊:
影响因子:
2.9
通讯作者:
Papin JA
中科院分区:
文献类型:
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作者:
Dillard LR;Payne DD;Papin JA
Microbial communities affect many facets of human health and well-being. Naturally occurring bacteria, whether in nature or the human body, rarely exist in isolation. A deeper understanding of the metabolic functions of these communities is now possible with emerging computational models. In this review, we summarize frameworks for constructing mechanistic models of microbial community metabolism and discuss available algorithms for model analysis. We highlight essential decision points that greatly influence algorithm selection, as well as model analysis. Polymicrobial metabolic models can be utilized to gain insights into host-pathogen interactions, bacterial engineering, and many more translational applications. Microbial communities affect many facets of human health and well-being. Naturally occurring bacteria, whether in nature or the human body, rarely exist in isolation.
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影响因子:
4.3
作者:
Fritzemeier CJ;Hartleb D;Szappanos B;Papp B;Lercher MJ
通讯作者:
Lercher MJ
影响因子:
4
作者:
Hadadi, Noushin;Pandey, Vikash;van der Meer, Jan R.
通讯作者:
van der Meer, Jan R.
DOI:
10.1038/nrmicro1949
发表时间:
2009-02
期刊:
Nature reviews. Microbiology
影响因子:
--
作者:
通讯作者:
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影响因子:
4.3
作者:
Brunner JD;Chia N
通讯作者:
Chia N
影响因子:
9.9
作者:
通讯作者:
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