Does active treatment in infants born at 22-23 weeks correlate with outcomes of more mature infants at the same hospital? An analysis of California NICU data, 2015-2019.
Does active treatment in infants born at 22-23 weeks correlate with outcomes of more mature infants at the same hospital? An analysis of California NICU data, 2015-2019.
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DOI：
10.1038/s41372-022-01381-x
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发表时间：
2022-10
影响因子：
2.9
通讯作者：
Lee, Henry C.
中科院分区：
文献类型：
--
作者：
Bane, Shalmali;Rysavy, Matthew A.;Carmichael, Suzan L.;Lu, Tianyao;Bennett, Mihoko;Lee, Henry C.
研究22-23周出生婴儿的住院积极治疗率是否与24-27周出生婴儿的生存率相关。我们纳入了2015-2019年在加州围产期质量护理合作医院分娩的所有妊娠22-27周的活产婴儿。我们评估了(1)22-23周婴儿的积极治疗（如气管插管、肾上腺素）与24-27周婴儿的存活至出院的相关性，以及(2)使用多层次模型的积极治疗与存活的关联。22-23周的积极治疗率与22-23周的婴儿结局相关，但与24-27周无关。积极治疗增加10%与24-25周（校正OR: 1.00 [95% CI: 0.95-1.05]）或26-27周的生存率（aOR: 1.02[0.95-1.09]）无关。22-23周出生的婴儿积极治疗的住院率与24-27周出生的婴儿存活率的提高无关。
To investigate whether hospital rates of active treatment for infants born at 22–23 weeks is associated with survival of infants born at 24–27 weeks. We included all liveborn infants 22–27 weeks of gestation delivered at California Perinatal Quality Care Collaborative hospitals from 2015–2019. We assessed (1) the correlation of active treatment (e.g., endotracheal intubation, epinephrine) in 22–23 week infants and survival until discharge for 24–27 week infants and (2) the association of active treatment with survival using multilevel models. The 22–23 week active treatment rate was associated with infant outcomes at 22–23 weeks but not 24–27 weeks. A 10% increase in active treatment did not relate to 24–25 week (adjusted OR: 1.00 [95% CI: 0.95–1.05]), or 26–27 week survival (aOR: 1.02 [0.95–1.09]). The hospital rate of active treatment for infants born at 22–23 weeks was not associated with improved survival for 24–27 week infants.
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影响因子：
2.9
作者：
Handley, S. C.;Steinhorn, R. H.;Lee, H. C.
通讯作者：
Lee, H. C.
影响因子：
7.2
作者：
Raju, Tonse N. K.;Mercer, Brian M.;Joseph, Gerald F., Jr.
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Joseph, Gerald F., Jr.
影响因子：
5.1
作者：
Hagadorn, James, I;Bennett, Mihoko, V;Lee, Henry C.
通讯作者：
Lee, Henry C.
影响因子：
26.1
作者：
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通讯作者：
Higgins, Rosemary D.
影响因子：
7.2
作者：
Hajdu, Sierra A.;Rossi, Robert M.;DeFranco, Emily A.
通讯作者：
DeFranco, Emily A.