Effectiveness and safety of acupuncture therapy for inflammatory bowel disease: a protocol of systematic review and meta-analysis.

Effectiveness and safety of acupuncture therapy for inflammatory bowel disease: a protocol of systematic review and meta-analysis.
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针灸治疗炎症性肠病的有效性和安全性:系统评价和荟萃分析方案

DOI:
10.1136/bmjopen-2020-045090
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发表时间:
2021-08-24
期刊:
影响因子:
2.9
通讯作者:
Liang FR
Liang FR
中科院分区:
医学3区
文献类型:
--
作者:
Zhou YF;Sun N;Cheng SR;Deng XD;Ye XY;Li ZJ;Zhou J;Xu GX;Qu YZ;Huang LY;Sun RR;Liang FR

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先前的评论表明,由于随机对照试验(RCT)有限,针灸治疗炎症性肠病(IBD)的有效性尚未得到充分证明。近年来,针灸治疗IBD的研究不断增多,使得进一步系统评价、综合更充分的临床数据来评价针灸治疗IBD的有效性和安全性成为可能。自建库至2021年3月,将检索Cochrane Library、MEDLINE、EMBASE、Ovid、联合与补充医学数据库、中国国家知识基础设施数据库、中国生物医学文献数据库、重庆中文科技期刊数据库、万方数据库等9个无语言限制的电子数据库。将包括针灸治疗 IBD 的随机对照试验。数据筛选、数据提取和风险偏倚评估将分别由两名评审员进行。将使用推荐评估、制定和评估应用程序的分级来评估证据的质量。如果在 RevMan 软件 (V.5.3) 上进行的异质性分析不显着,则将进行荟萃分析。主要结局是针灸治疗后甚至随访中症状的缓解。由于本次审查的数据不涉及患者信息和隐私,因此不需要伦理批准。结果将在同行评审期刊或相关会议上发表和传播。 CRD42020157903。
Previous reviews have suggested that the effectiveness of acupuncture for inflammatory bowel disease (IBD) has not well been demonstrated due to the limited randomised controlled trials (RCTs). In recent years, the growing research on acupuncture for IBD make it possible to conduct a further systematic review and synthesise more sufficient clinical data to evaluate the effectiveness and safety of acupuncture for IBD. Nine electronic databases without language restriction will be retrieved from inception to March 2021, including the Cochrane Library, MEDLINE, EMBASE, Ovid, the Allied and Complementary Medicine Database, China National Knowledge Infrastructure, Chinese Biomedical Literature Database, the Chongqing Chinese Science and Technology Periodical Database and Wanfang Database. The RCTs on acupuncture for IBD will be included. The data screening, data extraction and the assessment of risk bias will be performed respectively by two reviewers. The quality of evidence will be evaluated by using the Grading of recommendation Assessment, Development and Evaluation application. The meta-analysis will be performed if heterogeneity analysis conducted on the RevMan software (V.5.3) is insignificant. The primary outcome was symptoms alleviation after acupuncture treatment or even in the follow-up. Ethical approval will not be needed because data of this review are not involved in patient’s information and privacy. The results will be published and diffused in a peer-reviewed journal or relative conferences. CRD42020157903.
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