Infant overweight is associated with delayed motor development.
Infant overweight is associated with delayed motor development.
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DOI：
10.1016/j.jpeds.2009.12.054
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发表时间：
2010-07
期刊：
影响因子：
--
通讯作者：
Bentley M
中科院分区：
文献类型：
--
作者：
Slining M;Adair LS;Goldman BD;Borja JB;Bentley M
探讨婴儿超重和高皮下脂肪与婴儿运动发育的关系。参与者来自婴儿护理，喂养和肥胖风险项目，这是一项前瞻性，纵向研究，对3 - 18个月大的低收入非洲裔美国人母婴二人组进行评估（对217名婴儿进行836次观察）。暴露为超重（身长体重z评分≥ 2000 CDC/NCHS生长参考值的第90百分位数）和高皮下脂肪（三次皮褶厚度测量值之和>我们样本的第90百分位数）。运动发育采用Bayley婴儿发育量表-II进行评估。发育迟缓的特征是标准化的精神发育指数评分<85。纵向模型估计随时间变化的超重和皮下脂肪的功能，控制年龄和性别的发展成果。替代模型测试了并发和滞后关系（先前的体重或皮下脂肪预测当前的运动发育）。超重婴儿的运动延迟可能性是非超重婴儿的1.80倍（95% CI：1.09，2.97），高皮下脂肪婴儿的运动延迟可能性是低皮下脂肪婴儿的2.32倍（95% CI：1.26，4.29）。高皮下脂肪也与随后的运动发育延迟相关（OR=2.27，95%CI：1.08，4.76）。儿童超重和高皮下脂肪与婴儿运动发育延迟有关。
To examine how infant overweight and high subcutaneous fat relate to infant motor development. Participants are from the Infant Care, Feeding, and Risk of Obesity Project, a prospective, longitudinal study of low-income African American mother-infant dyads assessed from 3 -18 months of age (836 observations on 217 infants). Exposures were overweight (weight-for-length z-score ≥90th percentile of 2000 CDC/NCHS growth reference) and high subcutaneous fat (sum of three skinfold measurements >90th percentile of our sample). Motor development was assessed using Bayley Scales of Infant Development-II. Developmental delay was characterized as a standardized Psychomotor Development Index score <85. Longitudinal models estimated developmental outcomes as functions of time-varying overweight and subcutaneous fat, controlling for age and sex. Alternate models tested concurrent and lagged relationships (prior weight or subcutaneous fat predicting current motor development). Motor delay was 1.80 times as likely in overweight compared with non-overweight infants (95% CI:1.09, 2.97), and 2.32 times as likely in infants with high subcutaneous fat compared with lower subcutaneous fat (95% CI:1.26, 4.29). High subcutaneous fat was also associated with delay in subsequent motor development (OR=2.27, 95% CI:1.08, 4.76). Pediatric overweight and high subcutaneous fat are associated with delayed infant motor development.
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