Assessment of visual fixation in vegetative and minimally conscious states.
Assessment of visual fixation in vegetative and minimally conscious states.
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DOI：
10.1186/1471-2377-14-147
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发表时间：
2014-07-16
期刊：
影响因子：
2.6
通讯作者：
Laureys S
中科院分区：
文献类型：
--
作者：
Di H;Nie Y;Hu X;Tong Y;Heine L;Wannez S;Huang W;Yu D;He M;Thibaut A;Schnakers C;Laureys S
视觉注视在区分植物状态/无反应觉醒（VS/UWS）综合征和最低意识状态（MCS）中起着关键作用。然而，不同刺激的使用改变了患者发生视觉注视的频率，从而可能影响诊断的准确性。为了建立一个标准化的评估视觉注视的意识障碍（DOC）患者，我们比较了由镜子，球和光引起的视觉注视的频率。在诊断为MCS或VS/UWS的81例昏迷后患者中评估了视觉注视。采用卡方检验对不同刺激的注视发生率进行分析。81例患者中有40例（49%）表现出对视觉刺激的注视。在这些患者中，与球（23，28%）和镜子（20，25%）相比，镜子（39，48%）引起的视觉注视显著更多。与其他刺激相比，在视觉注视评估过程中使用镜子显示出更高的正反应率。因此，由镜子引起的注视可以是区分这两种意识障碍的非常敏感和准确的测试。
Visual fixation plays a key role in the differentiation between vegetative state/unresponsive wakefulness (VS/UWS) syndrome and minimally conscious state (MCS). However, the use of different stimuli changes the frequency of visual fixation occured in patients, thereby possibly affecting the accuracy of the diagnosis. In order to establish a standardized assessment of visual fixation in patients in disorders of consciousness (DOC), we compared the frequency of visual fixation elicited by mirror,a ball and a light. Visual fixation was assessed in eighty-one post-comatose patients diagnosed with a MCS or VS/UWS. Occurrence of fixation to different stimuli was analysis used Chi-square testing. 40 (49%) out of the 81 patients showed fixation to visual stimuli. Among those, significantly more patients (39, 48%) had visual fixation elicited by mirror compared to a ball (23, 28%) and mirror compared to a light (20, 25%). The use of a mirror during the assessment of visual fixation showed higher positive response rate, compared to other stimuli in eliciting a visual fixating response. Therefore, fixation elicited by a mirror can be a very sensitive and accurate test to differentiate the two disorders of consciousness.
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影响因子：
2.6
作者：
Bruno MA;Vanhaudenhuyse A;Schnakers C;Boly M;Gosseries O;Demertzi A;Majerus S;Moonen G;Hustinx R;Laureys S
通讯作者：
Laureys S
影响因子：
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作者：
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Estraneo, A.
DOI：
10.1016/j.apmr.2004.02.033
发表时间：
2004-12-01
影响因子：
4.3
作者：
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通讯作者：
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DOI：
10.1016/j.apmr.2010.07.218
发表时间：
2010-12-01
影响因子：
4.3
作者：
Seel, Ronald T.;Sherer, Mark;Zasler, Nathan
通讯作者：
Zasler, Nathan
影响因子：
2.6
作者：
Cheng L;Gosseries O;Ying L;Hu X;Yu D;Gao H;He M;Schnakers C;Laureys S;Di H
通讯作者：
Di H