Assessment of localisation to auditory stimulation in post-comatose states: use the patient's own name.

Assessment of localisation to auditory stimulation in post-comatose states: use the patient's own name.
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DOI:
10.1186/1471-2377-13-27
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发表时间:
2013-03-18
期刊:
影响因子:
2.6
通讯作者:
Di H
Di H
中科院分区:
医学4区
文献类型:
--
作者:
Cheng L;Gosseries O;Ying L;Hu X;Yu D;Gao H;He M;Schnakers C;Laureys S;Di H

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目前,对于如何在临床上评估昏迷恢复患者的声音定位还没有达成共识。在这里,我们研究了使用患者自己的名字与无意义的声音(即,铃声)进行听觉定位。86名被诊断为植物人状态/无反应觉醒综合症或最低意识状态的昏迷后患者被前瞻性纳入。听觉刺激的定位(即,头部或眼睛朝向声音)是使用患者自己的名字与铃声进行比较来评估的。统计分析使用带有Bonferroni校正的二项检验进行多重比较。在86例研究患者中,37例(43%)表现出对听觉刺激的定位。与声音(n=20,23%;p<0.001)相比,更多的患者(n=34,40%)将头或眼睛指向自己的名字。在评估意识障碍的听觉功能时,与中性声音相比,使用患者自己的名字更适合引起反应。
At present, there is no consensus on how to clinically assess localisation to sound in patients recovering from coma. We here studied auditory localisation using the patient’s own name as compared to a meaningless sound (i.e., ringing bell). Eighty-six post-comatose patients diagnosed with a vegetative state/unresponsive wakefulness syndrome or a minimally conscious state were prospectively included. Localisation of auditory stimulation (i.e., head or eyes orientation toward the sound) was assessed using the patient’s own name as compared to a ringing bell. Statistical analyses used binomial testing with bonferroni correction for multiple comparisons. 37 (43%) out of the 86 studied patients showed localisation to auditory stimulation. More patients (n=34, 40%) oriented the head or eyes to their own name as compared to sound (n=20, 23%; p<0.001). When assessing auditory function in disorders of consciousness, using the patient’s own name is here shown to be more suitable to elicit a response as compared to neutral sound.
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发表时间: 2002-12-01
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