Noninvasive temperature mapping with MRI using chemical shift water-fat separation.

Noninvasive temperature mapping with MRI using chemical shift water-fat separation.
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使用化学位移水脂肪分离的 MRI 无创温度测绘。

DOI:
10.1002/mrm.22310
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发表时间:
2010-05
影响因子:
3.3
通讯作者:
MacFall, James R.
MacFall, James R.
中科院分区:
医学3区
文献类型:
--
作者:
Soher, Brian J.;Wyatt, Cory;Reeder, Scott B.;MacFall, James R.

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同时含有水和脂质的组织,如乳腺,由于脂质质子中缺乏温度引起的频移,混淆了用于绘制温度的标准MR质子参考频移方法。广义的基于Dixon化学位移的水脂肪分离方法,如GE采用回声不对称和最小二乘估计方法对水和脂肪进行迭代分解,可以得到复杂的水和脂肪图像。一旦分离,水信号随时间的相位变化就可以用来绘制温度图。脂质信号的相位变化可以用来校正非温度相关的相位变化,如静态场漂移的振幅。在这项工作中,一种图像采集和后处理方法,称为水和脂肪热MRI,在含有30:70,50:50和70:30水脂肪体积的幻影中进行了演示。使用小环形相控射频阵列,在Off1-On-Off2模式下进行非侵入性加热,加热时间超过50分钟。温度变化参考了第一次图像采集。四根光纤温度探头被放置在假体内部进行温度比较。尽管实验过程中静态场漂移幅度很大,但与探针匹配的感兴趣区域(ROI)温度值显示出极好的一致性(全球平均值±标准差:−0.09±0.34°C)。
Tissues containing both water and lipids, e.g., breast, confound standard MR proton reference frequency-shift methods for mapping temperatures due to the lack of temperature-induced frequency shift in lipid protons. Generalized Dixon chemical shift–based water-fat separation methods, such as GE’s iterative decomposition of water and fat with echo asymmetry and least-squares estimation method, can result in complex water and fat images. Once separated, the phase change over time of the water signal can be used to map temperature. Phase change of the lipid signal can be used to correct for non-temperature-dependent phase changes, such as amplitude of static field drift. In this work, an image acquisition and postprocessing method, called water and fat thermal MRI, is demonstrated in phantoms containing 30:70, 50:50, and 70:30 water-to-fat by volume. Noninvasive heating was applied in an Off1-On-Off2 pattern over 50 min, using a miniannular phased radiofrequency array. Temperature changes were referenced to the first image acquisition. Four fiber optic temperature probes were placed inside the phantoms for temperature comparison. Region of interest (ROI) temperature values colocated with the probes showed excellent agreement (global mean ± standard deviation: −0.09 ± 0.34°C) despite significant amplitude of static field drift during the experiments.
DOI: 10.1158/1078-0432.ccr-04-0133
发表时间: 2004-07-01
影响因子: 11.5
作者:
Jones, EL;Prosnitz, LR;Vujaskovic, Z
通讯作者: Vujaskovic, Z
DOI: 10.1002/mrm.1185
发表时间: 2001-08-01
影响因子: 3.3
作者:
Griffin, JL;Williams, HJ;Nicholson, JK
通讯作者: Nicholson, JK
DOI: 10.1002/mrm.20624
发表时间: 2005-09-01
影响因子: 3.3
作者:
Reeder, SB;Pineda, AR;Pelc, NJ
通讯作者: Pelc, NJ
DOI: 10.1085/jgp.26.2.179
发表时间: 1942-11-20
期刊: The Journal of general physiology
影响因子: --
作者:
Lynn JG;Zwemer RL;Chick AJ;Miller AE
通讯作者: Miller AE
DOI: 10.1002/mrm.20146
发表时间: 2004-08-01
影响因子: 3.3
作者:
Ma, JF
通讯作者: Ma, JF