2012 Division of medicinal chemistry award address. Trekking the cannabinoid road: a personal perspective.
2012 Division of medicinal chemistry award address. Trekking the cannabinoid road: a personal perspective.
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DOI：
10.1021/jm500220s
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发表时间：
2014-05-22
影响因子：
7.3
通讯作者：
Makriyannis A
中科院分区：
文献类型：
--
作者：
Makriyannis A
我在大麻素领域的工作跨越了近三十年，涵盖了我科学生涯的主要部分。这也反映了生物学这一最初基本上未经探索的领域的强劲进展。在这段时间里，我见证了现代大麻素生物学的发展，从发现其两种受体开始，然后是其内源性配体的表征以及参与其生物合成和生物转化的酶系统的鉴定。我很幸运地开始在这个新时代的开始，并参与了一些新的发现。这是一段非常激动人心的旅程。通过涵盖我在“现代大麻素研究”期间工作的一些关键方面，这种观点，部分是历史性的，旨在说明该领域如何发展，关键发现以及未来最有希望的方向。
My involvement with the field of cannabinoids spans close to three decades, and covers a major part of my scientific career. It also reflects the robust progress in this initially largely unexplored area of biology. During this period of time, I have witnessed the growth of modern cannabinoid biology, starting from the discovery of its two receptors and followed by the characterization of its endogenous ligands and the identification of the enzyme systems involved in their biosynthesis and biotransformation. I was fortunate enough to start at the beginning of this new era and participate in a number of the new discoveries. It has been a very exciting journey. By covering some key aspects of my work during this period of “modern cannabinoid research,” this perspective, in part historical, intends to give an account of how the field grew, the key discoveries, and the most promising directions for the future.
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影响因子：
7.3
作者：
Alapafuja, Shakiru O.;Nikas, Spyros P.;Bharathan, Indu T.;Shukla, Vidyanand G.;Nasr, Mahmoud L.;Bowman, Anna L.;Zvonok, Nikolai;Li, Jing;Shi, Xiaomeng;Engen, John R.;Makriyannis, Alexandros
通讯作者：
Makriyannis, Alexandros
影响因子：
5
作者：
Calignano, A;LaRana, G;Piomelli, D
通讯作者：
Piomelli, D
DOI：
10.1073/pnas.0400997101
发表时间：
2004-06-08
影响因子：
11.1
作者：
Fegley, D;Kathuria, S;Piomelli, D
通讯作者：
Piomelli, D
影响因子：
3.3
作者：
Deng L;Guindon J;Vemuri VK;Thakur GA;White FA;Makriyannis A;Hohmann AG
通讯作者：
Hohmann AG
影响因子：
4.7
作者：
Gatley, SJ;Lan, R;Makriyannis, A
通讯作者：
Makriyannis, A