Direct optical imaging of graphene in vitro by nonlinear femtosecond laser spectral reshaping.
Direct optical imaging of graphene in vitro by nonlinear femtosecond laser spectral reshaping.
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非线性飞秒激光光谱重塑对石墨烯的直接光学成像。
DOI：
10.1021/nl303358p
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发表时间：
2012-11-14
期刊：
影响因子：
10.8
通讯作者：
Warren WS
中科院分区：
文献类型：
--
作者：
Li B;Cheng Y;Liu J;Yi C;Brown AS;Yuan H;Vo-Dinh T;Fischer MC;Warren WS
基于飞秒激光光谱整形的非线性光学显微镜，在载玻片和生物环境中对不同方法制成的石墨烯样品进行了表征和成像。该技术清楚地区分了具有不同层数的石墨烯薄片，并揭示了与机械剥离或化学气相沉积生长的石墨烯相比，还原的氧化石墨烯的独特的非线性光学性质。非线性使其适用于散射样品（如组织），而不是以前的方法，如传输。这一点通过对与石墨烯薄片一起孵育的乳腺癌细胞的高分辨率成像得到了证明。
Nonlinear optical microscopy, based on femtosecond laser spectral reshaping, characterized and imaged graphene samples made from different methods, both on slides and in a biological environment. This technique clearly discriminates between graphene flakes with different numbers of layers and reveals the distinct nonlinear optical properties of reduced graphene oxide as compared to mechanically exfoliated or chemical vapor deposition grown graphene. The nonlinearity makes it applicable to scattering samples (such as tissue) as opposed to previous methods, such as transmission. This was demonstrated by high-resolution imaging of breast cancer cells incubated with graphene flakes.
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