Central Role of Adenosine 5'-Phosphosulfate Reductase in the Control of Plant Hydrogen Sulfide Metabolism.
Central Role of Adenosine 5'-Phosphosulfate Reductase in the Control of Plant Hydrogen Sulfide Metabolism.
复制标题
DOI：
10.3389/fpls.2018.01404
复制
发表时间：
2018
影响因子：
5.6
通讯作者：
Zhang H
中科院分区：
文献类型：
--
作者：
Fu Y;Tang J;Yao GF;Huang ZQ;Li YH;Han Z;Chen XY;Hu LY;Hu KD;Zhang H
硫化氢(H_2S)被认为是继一氧化氮(NO)和一氧化碳(CO)之后动植物体内的第三种气体递质。本文综述了硫化氢在植物生长发育及对生物和非生物胁迫响应中的生理作用。产生硫化氢的酶受到严格的调节，在需要时产生硫化氢，有助于硫化氢对环境刺激的微妙反应。H_2S在植物硫代谢中占有中心地位，因为它是无机硫与第一个有机含硫化合物半胱氨酸的纽带，半胱氨酸是合成蛋氨酸、辅酶A、维生素等的起点。在硫同化过程中，腺苷5‘-磷酸硫酸盐还原酶(APR)是对硫同化途径控制最大的限速酶，可能是生成H_2S的关键成分。APR是一种进化上保守的蛋白质，在APR中发现了两个保守的结构域：PAPS_还原酶和硫氧还蛋白。硫酸盐还原包括APR催化步骤是在叶绿体中进行的。APR是硫磺同化的关键酶，主要由转录因子在转录水平上调节，以响应硫的有效性和环境刺激。番茄三个APR基因启动子区域的顺式作用元件表明，硫饥饿、细胞分裂素、CO2和病原菌等多种因素可能调节SLAPR的表达。综上所述，APR作为调节硫同化的关键酶，在植物对各种环境因子的响应过程中，可能对硫化氢的产生起着关键作用。
Hydrogen sulfide (H2S) has been postulated to be the third gasotransmitter in both animals and plants after nitric oxide (NO) and carbon monoxide (CO). In this review, the physiological roles of H2S in plant growth, development and responses to biotic, and abiotic stresses are summarized. The enzymes which generate H2S are subjected to tight regulation to produce H2S when needed, contributing to delicate responses of H2S to environmental stimuli. H2S occupies a central position in plant sulfur metabolism as it is the link of inorganic sulfur to the first organic sulfur-containing compound cysteine which is the starting point for the synthesis of methionine, coenzyme A, vitamins, etc. In sulfur assimilation, adenosine 5′-phosphosulfate reductase (APR) is the rate-limiting enzyme with the greatest control over the pathway and probably the generation of H2S which is an essential component in this process. APR is an evolutionarily conserved protein among plants, and two conserved domains PAPS_reductase and Thioredoxin are found in APR. Sulfate reduction including the APR-catalyzing step is carried out in chloroplasts. APR, the key enzyme in sulfur assimilation, is mainly regulated at transcription level by transcription factors in response to sulfur availability and environmental stimuli. The cis-acting elements in the promoter region of all the three APR genes in Solanum lycopersicum suggest that multiple factors such as sulfur starvation, cytokinins, CO2, and pathogens may regulate the expression of SlAPRs. In conclusion, as a critical enzyme in regulating sulfur assimilation, APR is probably critical for H2S generation during plants’ response to diverse environmental factors.
登录
查看更多内容
影响因子：
16
作者：
Jones-Rhoades, MW;Bartel, DP
通讯作者：
Bartel, DP
影响因子：
2.3
作者：
Kopriva, S;Hartmann, T;Rennenberg, H
通讯作者：
Rennenberg, H
影响因子：
7.4
作者：
Koprivova, A;Melzer, M;Kopriva, S
通讯作者：
Kopriva, S
影响因子：
3.5
作者：
Hatzfeld, Y;Lee, S;Saito, K
通讯作者：
Saito, K
影响因子：
6.9
作者：
Bloem, E;Riemenschneider, A;Schnug, E
通讯作者：
Schnug, E