The use of molecular methods in infectious diseases.

The use of molecular methods in infectious diseases.
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分子方法在传染病中的应用。

DOI:
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发表时间:
1992
影响因子:
158.5
通讯作者:
Lucy S. Tompkins
Lucy S. Tompkins
中科院分区:
医学1区
文献类型:
--
作者:
Lucy S. Tompkins

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近年来,临床期刊上出现了大量描述现代分子方法及其在临床医学中的应用的文章。本文综述了分子技术在传染病中的四种应用:它们可用于证明菌株之间的相关性,用于流行病学调查,阐明菌株的发病机制或毒性,促进临床诊断,并确定病因不明的综合征的因子。分子流行病学为了发现传染病爆发的原因,流行病学家需要尽早确定是否单一菌株(或类型)的微生物负责…
IN recent years a large number of articles have appeared in clinical journals describing contemporary molecular methods and their applications in clinical medicine. This review addresses four applications of molecular techniques in infectious diseases: they can be used to demonstrate relatedness between strains for epidemiologic investigations, to shed light on the pathogenesis or virulence of a strain, to facilitate the clinical diagnosis, and to identify the agents of syndromes whose causes are unknown. Molecular Epidemiology To find the cause of an infectious-disease outbreak, epidemiologists need to determine early on whether a single strain (or type) of microorganism is responsible for . . .
DOI: 10.7326/0003-4819-97-3-317
发表时间: 1982
影响因子: 39.2
作者:
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