Symptom Profiles and Progression in Hospitalized and Nonhospitalized Patients with Coronavirus Disease, Colorado, USA, 2020.
Symptom Profiles and Progression in Hospitalized and Nonhospitalized Patients with Coronavirus Disease, Colorado, USA, 2020.
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DOI：
10.3201/eid2702.203729
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发表时间：
2021-03
影响因子：
11.8
通讯作者：
Colorado Investigation Team2
中科院分区：
文献类型：
--
作者：
Vahey GM;Marshall KE;McDonald E;Martin SW;Tate JE;Midgley CM;Killerby ME;Kawasaki B;Herlihy RK;Alden NB;Staples JE;Colorado Investigation Team2
为了提高对冠状病毒病（COVID-19）的认识，并为临床和公共卫生指导提供信息，我们在科罗拉多随机选择了600名COVID-19病例患者。电话问卷记录了经历的症状，症状发生的时间以及每次持续的时间。在128例住院患者中，常见的症状包括发热（84%）、疲乏（83%）、咳嗽（73%）和呼吸困难（72%）。在236例非住院患者中，常见的症状包括疲劳（90%）、发热（83%）、咳嗽（83%）和肌痛（74%）。最常见的初始症状是咳嗽（21%-25%）和发热（20%-25%）。在多变量分析中，呕吐、呼吸困难、精神状态改变、脱水和喘息与住院显著相关，而流涕、头痛、咽喉痛和嗅觉丧失或味觉丧失与未住院显著相关。全身症状和上呼吸道症状出现较早，嗅觉丧失、味觉丧失、下呼吸道症状和胃肠道症状出现较晚。在对潜在COVID-19病例作出临床和公共卫生决策时，应将症状与其他流行病学因素一并考虑。
To improve recognition of coronavirus disease (COVID-19) and inform clinical and public health guidance, we randomly selected 600 COVID-19 case-patients in Colorado. A telephone questionnaire captured symptoms experienced, when symptoms occurred, and how long each lasted. Among 128 hospitalized patients, commonly reported symptoms included fever (84%), fatigue (83%), cough (73%), and dyspnea (72%). Among 236 nonhospitalized patients, commonly reported symptoms included fatigue (90%), fever (83%), cough (83%), and myalgia (74%). The most commonly reported initial symptoms were cough (21%–25%) and fever (20%–25%). In multivariable analysis, vomiting, dyspnea, altered mental status, dehydration, and wheezing were significantly associated with hospitalization, whereas rhinorrhea, headache, sore throat, and anosmia or ageusia were significantly associated with nonhospitalization. General symptoms and upper respiratory symptoms occurred earlier in disease, and anosmia, ageusia, lower respiratory symptoms, and gastrointestinal symptoms occurred later. Symptoms should be considered alongside other epidemiologic factors in clinical and public health decisions regarding potential COVID-19 cases.
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影响因子：
8.5
作者：
Adorni F;Prinelli F;Bianchi F;Giacomelli A;Pagani G;Bernacchia D;Rusconi S;Maggi S;Trevisan C;Noale M;Molinaro S;Bastiani L;Fortunato L;Jesuthasan N;Sojic A;Pettenati C;Tavio M;Andreoni M;Mastroianni C;Antonelli Incalzi R;Galli M
通讯作者：
Galli M
影响因子：
--
作者：
Bursac, Zoran;Gauss, C Heath;Williams, David Keith;Hosmer, David W
通讯作者：
Hosmer, David W
DOI：
10.15585/mmwr.mm6915e3
发表时间：
2020-04-17
期刊：
MMWR. Morbidity and mortality weekly report
影响因子：
--
作者：
Garg S;Kim L;Whitaker M;O'Halloran A;Cummings C;Holstein R;Prill M;Chai SJ;Kirley PD;Alden NB;Kawasaki B;Yousey-Hindes K;Niccolai L;Anderson EJ;Openo KP;Weigel A;Monroe ML;Ryan P;Henderson J;Kim S;Como-Sabetti K;Lynfield R;Sosin D;Torres S;Muse A;Bennett NM;Billing L;Sutton M;West N;Schaffner W;Talbot HK;Aquino C;George A;Budd A;Brammer L;Langley G;Hall AJ;Fry A
通讯作者：
Fry A
影响因子：
28.3
作者：
Gorbalenya, Alexander E.;Baker, Susan C.;Ziebuhr, John
通讯作者：
Ziebuhr, John
影响因子：
11.1
作者：
Lechien, Jerome R.;Chiesa-Estomba, Carlos M.;Saussez, Sven
通讯作者：
Saussez, Sven