A fatal case of hemophagocytic lymphohistiocytosis associated with gestational psittacosis without symptoms of pneumonia
A fatal case of hemophagocytic lymphohistiocytosis associated with gestational psittacosis without symptoms of pneumonia
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与妊娠期鹦鹉热相关的噬血细胞淋巴组织细胞增多症死亡一例,无肺炎症状
DOI:
10.1111/jog.15429
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发表时间:
2022
影响因子:
1.6
通讯作者:
Yanagihara Itaru
中科院分区:
文献类型:
--
作者:
Yoshimura Michinobu;Shimizu Kanako;Nakura Yukiko;Kawahara Kazumi;Katano Harutaka;Motooka Daisuke;Takeuchi Makoto;Nagamune Kisaburo;Imamura Yoshiaki;Nakamura Shota;Yasukawa Kiyoshi;Hasegawa Hideki;Yoshida Yoshio;Yanagihara Itaru
Psittacosis is a zoonotic infection caused byChlamydia psittaci. Most patients present with acute respiratory symptoms and systemic illness. WhenC. psittaciinfects pregnant women, it causes severe clinical manifestations called gestational psittacosis. Here we report a case of gestational psittacosis. Our patient lacked respiratory symptoms, and pathological postmortem examinations revealed severe placentitis. Both DNA and immunohistochemical analyses were positive forC. psittacifrom formalin‐fixed paraffin‐embedded tissues. The chlamydial DNA in the placenta was about 100 times more abundant than that in the lungs; therefore, the placenta rather than the lungs was the probable target of theC. psittaciinfection during this pregnancy. We could not identify the source of infection. Gestational psittacosis should be considered in the differential diagnosis for fever of unknown origin during pregnancy, even in cases lacking respiratory symptoms.
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