Substance Use and Healthcare Utilization Across the Pre-Exposure Prophylaxis (PrEP) Care Cascade among Black and Latino Men Who Have Sex with Men.
Substance Use and Healthcare Utilization Across the Pre-Exposure Prophylaxis (PrEP) Care Cascade among Black and Latino Men Who Have Sex with Men.
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DOI：
10.1080/10826084.2022.2108059
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发表时间：
2022
影响因子：
2
通讯作者：
Eaton, Lisa A.
中科院分区：
文献类型：
--
作者：
Watson, Ryan J.;Morgan, Ethan;Collibee, Charlene;Kalinowski, Jolaade;Cunningham, Casey;Edelman, E. Jennifer;Chan, Philip;Eaton, Lisa A.
尽管暴露前预防（PrEP）对HIV预防的有效性有文献记载，但黑人和拉丁裔/西班牙裔男男性行为者（BLMSM）在接受和坚持方面存在很大差异。有限的数据存在于BLMSM在PrEP护理级联的不同阶段物质使用的影响。我们研究了物质（酒精、大麻、其他药物）使用与PrEP护理级联（PrEP意识/不使用；PrEP使用/停止使用；PrEP使用/坚持使用）的相关方式。我们利用了2020年2月至10月收集的908名BLMSM（年龄= 25.17，范围：18-29）的全国样本的数据。我们发现，在所有物质使用测量中，更严重的酒精使用、更多的其他药物（如可卡因）使用、更多的参与者医疗保健利用以及更多的伴侣数量分别与更低的PrEP意识可能性相关。这些相同的因素也与更高的PrEP依从性可能性相关。相反，只有大麻的使用与PrEP的停止使用有关。虽然我们证实了一些早期的发现（即，酒精使用与PrEP中断和PrEP使用有关），但我们新发现大麻是坚持PrEP的障碍。我们的研究结果强调需要改进PrEP干预措施，以提高吸毒的BLMSM的认识，他们是艾滋病毒感染风险最高的人群。
Despite the documented efficacy of pre-exposure prophylaxis (PrEP) for HIV prevention, large disparities in uptake and adherence exist among Black and Latino/Hispanic men who have sex with men (BLMSM). Limited data exists among BLMSM on the impact of substance use at different stages of the PrEP Care Cascade. We examined the ways substance (alcohol, cannabis, other drug) use is related to PrEP experiences across the PrEP Care Cascade (PrEP aware/no use; PrEP use/discontinuation; PrEP use/adherent) We utilized data from a national sample of 908 BLMSM (Mage = 25.17, range: 18-29), collected between February and October 2020. We found that heavier alcohol use, more other drug (e.g., cocaine) use, more participant healthcare utilization, and higher number of partners across all measures of substance use were separately associated with a lower likelihood of being aware of PrEP. These same factors were also associated with a higher likelihood of PrEP adherence. Conversely, only cannabis use was associated with discontinuation of PrEP use. While we confirm some earlier findings (i.e., alcohol use is associated with both PrEP discontinuation and PrEP use), we newly identify cannabis as a barrier to the adherence of PrEP. Our findings highlight the need for improved PrEP interventions to increase awareness among BLMSM with substance use who are among the most at-risk for HIV infection.
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影响因子：
3.8
作者：
Lancki, Nicola;Almirol, Ellen;Schneider, John A.
通讯作者：
Schneider, John A.
影响因子：
1.7
作者：
Cahill S;Taylor SW;Elsesser SA;Mena L;Hickson D;Mayer KH
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Mayer KH
影响因子：
3.7
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García M;Harris AL
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Harris AL
影响因子：
4.4
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Parsons JT
影响因子：
4.4
作者：
Calabrese SK;Earnshaw VA;Krakower DS;Underhill K;Vincent W;Magnus M;Hansen NB;Kershaw TS;Mayer KH;Betancourt JR;Dovidio JF
通讯作者：
Dovidio JF