How does moxibustion possibly work?
How does moxibustion possibly work?
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DOI：
10.1155/2013/198584
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发表时间：
2013
期刊：
影响因子：
--
通讯作者：
Chiu JH
中科院分区：
文献类型：
--
作者：
Chiu JH
“针灸”是“针灸”和“艾灸”的混合词，更接近于这种治疗的中文表意文字。西方国家的人们对针灸更熟悉，而艾灸则不太受欢迎，部分原因是科学研究的缺乏。虽然艾灸的循证疗效有待进一步阐明，但艾灸可能发挥作用的机制包括温度相关和非温度相关机制。局部躯体刺激（LSTS），一种类型的艾灸，是通过应用热源和以上的穴位。这种温和的热刺激穴位引起皮肤损伤很小，与艾灸的燃烧效果相反，但确实引起内脏的轻度氧化应激。因此，在动物的外周穴位LR 14和PC 6处预处理的LSTS能够诱导内脏HSP70的表达，并保护肝脏和心脏免受缺血再灌注损伤。与温度无关的机制包括烟雾、草药和生物物理（远红外）刺激。我们的结论是，LSTS，远程预处理方法，具有潜在的临床实用性。然而，需要进行涉及大规模临床试验的循证有效性和安全性研究，以便这种方法能够获得西方科学家的认可。
“Acupmoxa” is a hybrid word of “acupuncture” and “moxibustion” that more closely resembles the Chinese ideograph for this treatment. People in Western countries are more familiar with acupuncture, while moxibustion is less popular, partially due to the paucity of scientific studies. Although the evidence-based efficacy of moxibustion needs to be further clarified, the mechanisms by which moxibustion may work include temperature-related and nontemperature-related ones. Local somatothermal stimulation (LSTS), one type of moxibustion, is achieved by application of a heat source to and above the acupoint. Such mild heat stimulation of the acupoint induces little skin damage, in contrast to the burning effect of moxibustion, but does provoke mild oxidative stress in the viscera. Thus, preconditioned LSTS at the peripheral acupoints LR 14 and PC 6 of animals is able to induce visceral HSP70 expression and to protect the liver and the heart against ischemia-reperfusion injury. Nontemperature-related mechanisms include smoke, herbs, and biophysical (far infrared) stimulation. We conclude that LSTS, a remote preconditioning method, has potential clinical usefulness. However, evidence-based efficacy and safety studies involving large-scaled clinical trials are needed in order that this approach will pass muster with Western scientists.
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影响因子：
8.2
作者：
Chang, SL;Lin, JG;Cheng, JT
通讯作者：
Cheng, JT
DOI：
10.1302/0301-620x.84b8.9362
发表时间：
2002-11-01
影响因子：
--
作者：
Bushell, AJ;Klenerman, L;Jackson, MJ
通讯作者：
Jackson, MJ
影响因子：
3.1
作者：
Chiu, JH;Kuo, YL;Hong, CY
通讯作者：
Hong, CY
影响因子：
5
作者：
Gill, RR;Gbur, CJ;Sholley, MM
通讯作者：
Sholley, MM
影响因子：
120.7
作者：
Cardini, F;Huang, WX
通讯作者：
Huang, WX