The Mouse Genome Database (MGD): updates and enhancements.

The Mouse Genome Database (MGD): updates and enhancements.
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DOI:
10.1093/nar/gkj085
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发表时间:
2006-01-01
影响因子:
14.9
通讯作者:
Mouse Genome Database Group
Mouse Genome Database Group
中科院分区:
生物学2区
文献类型:
--
作者:
Blake JA;Eppig JT;Bult CJ;Kadin JA;Richardson JE;Mouse Genome Database Group

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小鼠基因组数据库(MGD)整合了小鼠的遗传和基因组数据,以促进将小鼠用作理解人类生物学和疾病过程的模型系统。 MGD工作的一个核心组成部分是关于小鼠基因和基因产物的基因组,遗传,功能和表型信息的获取和整合。 MGD在更广泛的生物信息学界工作,以定义参考和语义标准,以促进资源之间的数据交换,包括从生物医学文献中纳入信息。 MGD还是集成生物学数据的计算评估的平台,其目的是识别与复杂表型相关的候选基因。 MGD可以在网上访问。此处描述的MGD的最新改进包括合并交互式基因组浏览器,表型资源的增强以及功能注释资源的进一步发展。
The Mouse Genome Database (MGD) integrates genetic and genomic data for the mouse in order to facilitate the use of the mouse as a model system for understanding human biology and disease processes. A core component of the MGD effort is the acquisition and integration of genomic, genetic, functional and phenotypic information about mouse genes and gene products. MGD works within the broader bioinformatics community to define referential and semantic standards to facilitate data exchange between resources including the incorporation of information from the biomedical literature. MGD is also a platform for computational assessment of integrated biological data with the goal of identifying candidate genes associated with complex phenotypes. MGD is web accessible at . Recent improvements in MGD described here include the incorporation of an interactive genome browser, the enhancement of phenotype resources and the further development of functional annotation resources.
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