Prostate cancer survival in the United States by race and stage (2001-2009): Findings from the CONCORD-2 study.
Prostate cancer survival in the United States by race and stage (2001-2009): Findings from the CONCORD-2 study.
复制标题
作者：
Steele CB;Li J;Huang B;Weir HK
在美国，1990年至1994年诊断的前列腺癌的5年相对生存率非常高（92%）;然而，黑人男性的生存率比白色男性低7%。作者更新了这些发现，并按阶段和种族检查了生存率。作者使用了CONCORD-2研究中37个州被诊断患有前列腺癌的男性（年龄15-99岁）的数据，覆盖了美国80%的人口。使用特定州和特定种族的生命表对生存率进行背景死亡率（净生存率）调整，并进行年龄标准化。提供了2001年至2003年和2004年至2009年的数据，以说明收集SEER汇总阶段2000的变化。在2001年至2009年诊断的1，527，602例前列腺癌中，黑人男性的局部病例比例从73%增加到77%，白色男性从77%增加到79%。尽管黑人男性远距离感染的比例高于白色男性，但在2004年至2009年期间，这两个群体中的远距离感染病例均不到6%。2004年至2009年，两个种族组的局部化阶段净生存率均超过99%。总体而言，在大多数州，5年净生存率超过95%。自第一次CONCORD研究以来，前列腺癌生存率有所增加，种族差距缩小。早期发现局部癌症可能有助于这一发现。然而，在总生存率方面也观察到种族差异。为了帮助了解哪些因素可能导致这种差异的持续存在，各州可以使用当地数据来探索社会人口特征，例如幸存者的健康保险状况，健康素养，治疗决策过程和治疗偏好。
The 5-year relative survival for prostate cancers diagnosed between 1990 and 1994 in the United States was very high (92%); however, survival in black males was 7% lower compared with white males. The authors updated these findings and examined survival by stage and race. The authors used data from the CONCORD-2 study for males (ages 15–99 years) who were diagnosed with prostate cancer in 37 states, covering 80% of the US population. Survival was adjusted for background mortality (net survival) using state-specific and race-specific life tables and was age-standardized. Data were presented for 2001 through 2003 and 2004 through 2009 to account for changes in collecting SEER Summary Stage 2000. Among the 1,527,602 prostate cancers diagnosed between 2001 and 2009, the proportion of localized cases increased from 73% to 77% in black males and from 77% to 79% in white males. Although the proportion of distant-stage cases was higher among black males than among white males, they represented less than 6% of cases in both groups between 2004 and 2009. Net survival exceeded 99% for localized stage between 2004 and 2009 in both racial groups. Overall, and in most states, 5-year net survival exceeded 95%. Prostate cancer survival has increased since the first CONCORD study, and the racial gap has narrowed. Earlier detection of localized cancers likely contributed to this finding. However, racial disparities also were observed in overall survival. To help understand which factors might contribute to the persistence of this disparity, states could use local data to explore sociodemographic characteristics, such as survivors’ health insurance status, health literacy, treatment decision-making processes, and treatment preferences.
登录
查看更多内容
影响因子：
10.3
作者：
Hankey, BF;Feuer, EJ;Kaplan, RS
通讯作者：
Kaplan, RS
影响因子：
254.7
作者：
DeSantis, Carol E.;Siegel, Rebecca L.;Jemal, Ahmedin
通讯作者：
Jemal, Ahmedin
影响因子：
5.7
作者：
Hoffman, RM;Harlan, LC;Potosky, AL
通讯作者：
Potosky, AL
影响因子：
6.2
作者：
Denberg, TD;Beaty, BL;Steiner, JF
通讯作者：
Steiner, JF
影响因子：
8.4
作者：
Corazziari, I;Quinn, M;Capocaccia, R
通讯作者：
Capocaccia, R