Human T-Lymphotropic Virus

Human T-Lymphotropic Virus
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人类嗜T淋巴细胞病毒

DOI:
--
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发表时间:
2013
期刊:
Neuroviral Infections
影响因子:
--
通讯作者:
H. Hara
H. Hara
中科院分区:
--
文献类型:
--
作者:
M. Yukitake;H. Hara

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我们报告了一个罕见的病例HTLV-1相关的原发性胃淋巴瘤。一名65岁男性因上腹部不适入院,内镜检查和上消化道系列检查发现胃中部三分之一处有不规则隆起病变,组织学研究显示T细胞型淋巴瘤。血清抗HTLV-1抗体阳性。CT和镓碘造影显示无淋巴结肿大或转移到其他器官。我们进行了全胃切除术,脾切除术,胆囊切除术和D2淋巴结清扫术。HTLV-1前病毒DNA在切除标本中为阳性,而在骨髓中为阴性。外周血和骨髓中异常淋巴细胞均为阴性。我们诊断这是一例HTLV-1相关的原发性胃淋巴瘤,这是一种非常罕见的病例,目前尚无治疗方案。进一步积累案例,应该有助于解决这个问题。
We reported a rare case of HTLV-1-associated primary gastric lymphoma. A 65-year-old man admitted for epigastric discomfort was found in endoscopic examination and an upper gastrointestinal series to have an irregular elevated lesion in the middle third of the stomach, and histological study showed T-cell type lymphoma. Anti-HTLV-1 antibody was positive in serum. CT and galium scintigraphy showed no lymph node swelling or metastasis to other organs. We conducted total gastrectomy, splenectomy, and cholecystectomy with D2 lymph node dissection. HTLV-1 pro-viral DNA was positive in the resected specimen, but negative in bone marrow. Abnormal lymphocytes were negative in peripheral blood and bone marrow. We diagnosed this as a case of HTLV-1-associated primary gastric lymphoma, a very rare occurrence with no treatment strat-egy yet established. Further accumulation of cases should help solve this problem.
旧金山静脉吸毒者中人类 T 细胞淋巴细胞病毒 I 型和 II 型:与血清阳性相关的危险因素。
DOI: 10.1093/infdis/164.1.36
发表时间: 1991
期刊: The Journal of infectious diseases
影响因子: --
作者:
Feigal,E;Murphy,E;Vranizan,K;Bacchetti,P;Chaisson,R;Drummond,JE;Blattner,W;McGrath,M;Greenspan,J;Moss,A
通讯作者: Moss,A
DOI: 10.1182/blood.v99.1.88
发表时间: 2002-01-01
期刊: BLOOD
影响因子: 20.3
作者:
Yamano, Y;Nagai, M;Jacobson, S
通讯作者: Jacobson, S