Patients' reaction to the disclosure of rare dreaded adverse events.

Patients' reaction to the disclosure of rare dreaded adverse events.
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患者对罕见的可怕不良事件的披露的反应。

DOI:
10.1016/j.pec.2010.07.014
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发表时间:
2011
影响因子:
3.5
通讯作者:
Peters,Ellen
Peters,Ellen
中科院分区:
医学2区
文献类型:
--
作者:
Fraenkel,Liana;Peters,Ellen

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背景:医生必须经常告知患者罕见但严重的不良事件(ae)的风险。目的探讨患者对罕见ae披露的反应。方法门诊患者观看了一段医生描述与罕见AE相关的药物的视频。然后,受试者对他们的担忧程度、发生不良反应的可能性以及服用药物的意愿进行评分。结果与白人男性相比,非白人男性更有可能认为发生AE的机会更大[校正优势比(95% CI)=3.37 (1.09-10.45)];与白人男性相比,白人女性更有可能担心[2.00(0.95-4.24)]、更有可能发生AE[6.22(2.50-15.50)]、更有可能发生AE[6.27(2.43-16.15)]、更不愿意服药[0.23(0.09-0.59)]。结论性别和种族影响患者对罕见但严重的不良反应的反应。实践意义需要更好地了解患者的风险认知,为制定最佳实践提供信息,以改善风险沟通。
BACKGROUNDPhysicians must frequently inform their patients of the risks of rare, but serious, adverse events (AEs).OBJECTIVETo examine how patients react to the disclosure of rare AEs.METHODSOutpatients viewed a video of a physician describing a medication associated with a rare AE. Subjects then rated their worry, perceived chance of developing the AE, and willingness to take the medication.RESULTSNon-White men were more likely to perceive a greater chance of developing the AE compared to White men [Adjusted odds ratio (95% CI)=3.37 (1.09–10.45)]; White women were more likely to be worried [2.00 (0.95–4.24)] and to perceive a greater chance of developing the [6.22 (2.50–15.50)], perceive a greater chance of developing the AE [6.27 (2.43–16.15)], and be less willing to take the medication [0.23 (0.09–0.59)], compared to White men.CONCLUSIONSGender and ethnicity influence how patients react to disclosure of rare, but serious, AEs.PRACTICE IMPLICATIONSAn improved understanding of patients’ risk perceptions is required to inform the development of best practices to improve risk communication.
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