Detection of RNA Modifications by HPLC Analysis and Competitive ELISA
Detection of RNA Modifications by HPLC Analysis and Competitive ELISA
复制标题
通过 HPLC 分析和竞争性 ELISA 检测 RNA 修饰
DOI:
10.1007/978-1-4939-0882-0_1
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发表时间:
2014
期刊:
影响因子:
--
通讯作者:
S. Bauer
中科院分区:
文献类型:
--
作者:
A. Kaufmann;S. Bauer
Over 100 different RNA modifications exist that are introduced posttranscriptionally by enzymes at specific nucleotide positions. Ribosomal RNA (rRNA) and transfer RNA (tRNA) exhibit the most and diverse modifications that presumably optimize their structure and function. In contrast, oxidative damage can lead to random modifications in rRNA and messenger RNA (mRNA) that strongly impair functionality. RNA modifications have also been implicated in avoiding self-RNA recognition by the immune system or immune evasion by pathogens. Here, we describe the detection of RNA modifications by HPLC analysis and competitive ELISA.
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影响因子:
3.2
作者:
De Bie, LGS;Roovers, M;Bujnicki, JM
通讯作者:
Bujnicki, JM
影响因子:
14.9
作者:
Persson, BC;Jager, G;Gustafsson, C
通讯作者:
Gustafsson, C
影响因子:
3.2
作者:
Glenn R. Bjurk
通讯作者:
Glenn R. Bjurk
DOI:
10.1016/s0378-4347(96)00351-9
发表时间:
1997
期刊:
Journal of chromatography. B, Biomedical sciences and applications
影响因子:
--
作者:
L. Snyder
通讯作者:
L. Snyder
DOI:
10.1271/bbb1961.38.785
发表时间:
1974
期刊:
Agricultural and biological chemistry
影响因子:
--
作者:
M. Fujimoto;A. Kuninaka;H. Yoshino
通讯作者:
H. Yoshino