Current cannabis use and smoking cessation among treatment seeking combustible smokers.
Current cannabis use and smoking cessation among treatment seeking combustible smokers.
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DOI：
10.1016/j.drugalcdep.2020.107928
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发表时间：
2020-04-01
影响因子：
4.2
通讯作者：
Zvolensky MJ
中科院分区：
文献类型：
--
作者：
Rogers AH;Shepherd JM;Buckner JD;Garey L;Manning K;Orr MF;Schmidt NB;Zvolensky MJ
吸食可燃烟草和使用大麻经常同时发生，这两种物质的使用与烟草和大麻相关问题的总体严重性有关。观察性工作发现，大麻的使用与戒烟失败有关，但缺乏直接测试戒烟治疗期间大麻使用对戒烟的纵向关联的研究。目前的研究审查了目前大麻使用对可燃烟草戒烟结果的影响。207名每日吸烟者（法师= 38.24岁，SD = 14.84，48.1%男性）参加了一项随机对照戒烟试验。生存分析和多水平建模用于评估通过12周随访的失效和复发行为。目前的研究是一项二级数据分析。目前的研究结果表明，与只吸烟的可燃烟草吸烟者相比，大麻的使用与更快的失效时间（OR = 0.644，se = 0.188，p = 0.019）有关，但与复发无关（OR =-0.218，se = 0.403，p = 0.525）。此外，在12周随访期间，大麻使用与实现任何7天点戒烟率的可能性较低相关（B = 0.93，se = 0.24，p = 0.0001）。目前的研究提供了新的证据，表明大麻的使用可能与可燃烟草的使用有关，因为在戒烟治疗后，大麻的使用时间更快，任何7天时间点戒烟率的可能性更低。开发大麻-烟草综合戒烟治疗是重点研究烟草-大麻使用的重要下一步。
Combustible tobacco smoking and cannabis use frequently occur together, and the use of both substances is associated with overall greater severity of tobacco and cannabis related problems. Observational work has found that cannabis use is associated with tobacco cessation failure, but research directly testing the longitudinal associations of cannabis use on tobacco cessation during smoking cessation treatment is lacking. The current study examined the impact of current cannabis use on combustible tobacco cessation outcomes. 207 daily combustible tobacco smokers (Mage = 38.24 years, SD = 14.84, 48.1% male) were enrolled in a randomized controlled smoking cessation trial. Survival analyses and multi-level modeling were used to assess lapse and relapse behavior through 12-week follow up. The current study is a secondary data analysis. Results of the current study suggest that cannabis use is associated with faster time to lapse (OR = .644, se = .188, p = .019), but not relapse (OR = −.218, se = .403, p = .525), compared to combustible tobacco-only smokers. Additionally, cannabis use was associated with lower likelihood of achieving any 7-day point prevalence abstinence during the 12 week follow up (b = 0.93, se =0 .24, p = 0.0001). The current study provides novel evidence that cannabis use may be related to combustible tobacco use in terms of faster time to lapse and lower likelihood of any 7-day point prevalence abstinence following smoking cessation treatment. Developing integrated cannabis-tobacco cessation treatments is an important next step in research focused on tobacco-cannabis use.
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