Sleep of critically ill children in the pediatric intensive care unit: a systematic review.
Sleep of critically ill children in the pediatric intensive care unit: a systematic review.
复制标题
小儿重症监护病房重症儿童的睡眠：系统评价。
DOI：
10.1016/j.smrv.2013.02.002
复制
发表时间：
2014-04
影响因子：
10.5
通讯作者：
Punjabi, Naresh M.
中科院分区：
文献类型：
--
作者：
Kudchadkar, Sapna R.;Aljohani, Othman A.;Punjabi, Naresh M.
儿科重症监护室（PICU）中的危重儿童暴露于多种物理，环境和药理学因素，这些因素增加了睡眠中断和丧失的倾向，并可能反过来在危重疾病的短期恢复和长期神经认知结果中发挥作用。机械通气的儿童接受镇静和镇痛药物，通常是高剂量和长时间，以改善舒适度和与机械通气的同步性。镇静剂和镇痛剂会减少慢波睡眠和快速眼动睡眠。奇怪的是，在重症儿童中，镇静药物剂量通常会增加，以改善镇静和睡眠的主观评估，导致进一步的躁动和睡眠质量的恶化。在PICU中遇到的年龄和危重疾病的异质性对这种环境下的睡眠研究提出了一些挑战。本文回顾了有关入住PICU的危重儿童睡眠的现有证据，重点介绍了所使用的主观和客观睡眠评估方法以及研究的特殊人群，包括机械通气儿童和严重烧伤儿童。
Critically ill children in the Pediatric Intensive Care Unit (PICU) are exposed to multiple physical, environmental and pharmacologic factors which increase the propensity for sleep disruption and loss and may, in turn, play a role in short-term recovery from critical illness and long-term neurocognitive outcomes. Mechanically ventilated children receive sedative and analgesic medications, often at high doses and for long durations, to improve comfort and synchrony with mechanical ventilation. Sedatives and analgesics can decrease slow wave sleep and rapid eye movement sleep. Paradoxically, sedative medications doses are often increased in critically ill children to improve the subjective assessment of sedation and sleep, leading to further agitation and deterioration of sleep quality. The heterogeneity in age and critical illness encountered in the PICU pose several challenges to research on sleep in this setting. The present article reviews the available evidence on sleep in critically ill children admitted to the PICU, with an emphasis on subjective and objective methods of sleep assessment used and special populations studied, including mechanically ventilated children and children with severe burns.
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DOI：
10.1164/ajrccm.163.2.9912128
发表时间：
2001-02-01
影响因子：
24.7
作者：
Freedman, NS;Gazendam, J;Schwab, RJ
通讯作者：
Schwab, RJ
DOI：
10.3109/01460869609026852
发表时间：
1996-01-01
期刊：
Issues in comprehensive pediatric nursing
影响因子：
--
作者：
Corser, N C
通讯作者：
Corser, N C
DOI：
10.1016/0013-4694(83)90276-6
发表时间：
1983-01-01
期刊：
ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY
影响因子：
--
作者：
JOHNSON, LC;SPINWEBER, CL;DEMENT, WC
通讯作者：
DEMENT, WC
影响因子：
5.6
作者：
COBLE, PA;KUPFER, DJ;KANE, J
通讯作者：
KANE, J
影响因子：
6
作者：
Frisk, U;Olsson, J;Hahn, RG
通讯作者：
Hahn, RG