Human herpesvirus 6-meningoencephalitis in an HIV patient with progressive multifocal leukoencephalopathy
Human herpesvirus 6-meningoencephalitis in an HIV patient with progressive multifocal leukoencephalopathy
复制标题
患有进行性多灶性白质脑病的 HIV 患者中的人类疱疹病毒 6-脑膜脑炎
DOI：
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发表时间：
2000
影响因子：
12.7
通讯作者：
James M. Powers
中科院分区：
文献类型：
--
作者：
Masumi Ito;J. V. Baker;David J. Mock;Andrew D. Goodman;Benjamin M. Blumberg;D. A. Shrier;James M. Powers
Abstract Human herpesvirus 6 (HHV6) has been reported as a rare cause of meningoencephalitis and leukoencephalitis. We present an HIV-infected patient with ¶lesions of progressive multifocal leukoencephalopathy (PML), but also meningoencephalitis apparently due to HHV6. Immunohistochemistry for HHV6 antigens and in situ polymerase chain reaction for HHV6 genome showed many positive lymphocytes and microglia in the meningeal and cortical lesions. More importantly, dead and dying neurons were conspicuous; some were undergoing neuronophagia and some displayed evidence of HHV6 infection. A pathogenic role for this almost universal, and usually commensal, virus in inflammatory brain lesions and PML is briefly discussed.
影响因子：
3.3
作者：
VINTERS, HV;WANG, R;WILEY, CA
通讯作者：
WILEY, CA
影响因子：
3.2
作者：
Albright, AV;Lavi, E;González-Scarano, F
通讯作者：
González-Scarano, F
人类疱疹病毒 6 型与进行性多灶性白质脑病脱髓鞘病变的关联。
DOI：
10.3109/13550289909029477
发表时间：
1999
期刊：
Journal of neurovirology.
影响因子：
--
作者：
Mock,DJ;Powers,JM;Goodman,AD;Blumenthal,SR;Ergin,N;Baker,JV;Mattson,DH;Assouline,JG;Bergey,EJ;Chen,B;Epstein,LG;Blumberg,BM
通讯作者：
Blumberg,BM