Long-term prognostic impact of the attenuated plaque in patients with acute coronary syndrome
Long-term prognostic impact of the attenuated plaque in patients with acute coronary syndrome
复制标题
衰减斑块对急性冠状动脉综合征患者的长期预后影响
DOI：
10.1007/s00380-014-0575-7
复制
发表时间：
2014
影响因子：
1.5
通讯作者：
Kiyoshi Yoshida
中科院分区：
文献类型：
--
作者：
H. Okura;T. Kataoka;M. Yoshiyama;J. Yoshikawa;Kiyoshi Yoshida
几项血管内超声研究报道，罪犯病变衰减斑块（AP）与经皮冠状动脉介入治疗（PCI）后的慢血流/无复流有关。AP的长期预后影响尚不清楚。本研究的目的是调查急性冠状动脉综合征（ACS）患者AP的急性和长期临床影响。共入组了110例成功接受PCI的ACS患者。比较AP患者（AP组：n= 73）和非AP患者（非AP组：n= 37）的急性和长期临床结局。长期心脏事件定义为死亡和ACS的复合事件。两组的基线特征相似。AP与首次球囊充盈后即刻的TIMI帧数较高相关。血栓切除术和冠状动脉内给药后，AP组和非AP组的最终TIMI帧数相似。虽然AP与住院期间致死性心律失常的发生率较高相关，但两组之间的住院死亡率没有差异。在随访期间（中位数6.2年），两组之间的无心脏事件生存率没有差异。尽管对冠状动脉复流的初始不利影响，但AP的存在并不影响ACS患者的急性和长期临床结局。
Several intravascular ultrasound studies have reported that culprit lesion-attenuated plaque (AP) is related to slow flow/no reflow after percutaneous coronary intervention (PCI). Long-term prognostic impact of the AP is unknown. The aim of this study was to investigate acute and long-term clinical impact of the AP in patients with acute coronary syndrome (ACS). A total of 110 ACS patients who underwent successful PCI were enrolled. Acute and long-term clinical outcomes were compared between patients with AP (AP group:n= 73) and those without AP (non-AP group:n= 37). Long-term cardiac event was defined as a composite of death and ACS. Baseline characteristics in 2 groups were similar. AP was associated with higher TIMI frame count immediately after the first balloon inflation. After thrombectomy and intracoronary drug administration, final TIMI frame count became similar between AP and non-AP group. Although AP was associated with higher incidence of fatal arrhythmia during hospitalization, in-hospital mortality did not differ between the 2 groups. During follow-up (median 6.2 years), cardiac event-free survival did not differ between the 2 groups. Despite the initial unfavorable effect on coronary reflow, presence of AP did not affect acute as well as long-term clinical outcome in patients with ACS.
影响因子：
24
作者：
Kawamoto, Takahiro;Okura, Hiroyuki;Yoshida, Kiyoshi
通讯作者：
Yoshida, Kiyoshi
虚拟组织学血管内超声定义的靶病灶薄帽纤维粥样斑块对心绞痛患者经皮冠状动脉介入治疗期间微血管损伤的影响
影响因子：
3.3
作者：
Yamada R;Okura H;Neishi Y;Kawamoto T;Yoshida K;et al.
通讯作者：
et al.
影响因子：
14
作者：
Miyamoto, Yoshinori;Okura, Hiroyuki;Yoshida, Kiyoshi
通讯作者：
Yoshida, Kiyoshi