Changes of β‐Endorphin and Met‐Enkephalin Content in the Hypothalamus‐Pituitary Axis Induced by Aging
Changes of β‐Endorphin and Met‐Enkephalin Content in the Hypothalamus‐Pituitary Axis Induced by Aging
复制标题
衰老引起的下丘脑-垂体轴β-内啡肽和蛋氨酸脑啡肽含量的变化
DOI：
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发表时间：
1983
影响因子：
4.7
通讯作者：
M. Trabucchi
中科院分区：
文献类型：
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作者：
Cristina Missale;Stefano Govoni;L. Croce;A. Bosio;P. Spano;M. Trabucchi
翻译后摘要：β-内啡肽-和甲硫氨酸-脑啡肽-免疫反应物质的量较高，在老年大鼠的垂体。然而，衰老过程降低了下丘脑中β内啡肽的含量，但不影响甲硫氨酸脑啡肽免疫反应物质的含量。因此，这两个领域的调节机制似乎受到年龄增长的不同影响。另一方面，这些肽的垂体增加与老年人对压力的激素反应受损的假设一致。
Abstract: The amounts of β‐endorphin‐ and Met‐enkephalin‐immunoreactive material are higher in the pituitary of aged rats. However, the aging process decreases the content of βendophin‐, but does not affect that of Met‐enkephalin‐immunoreactive material, in hypothalamus. Thus, it seems that the regulatory mechanisms in the two areas are differentially affected by increasing age. On the other hand, the pituitary increase of these peptides is in line with the assumption that in the elderly the hormonal response to stress is impaired.
影响因子：
56.9
作者：
GIBSON, GE;PETERSON, C;JENDEN, DJ
通讯作者：
JENDEN, DJ