Maize centromeres: where sequence meets epigenetics
Maize centromeres: where sequence meets epigenetics
复制标题
玉米着丝粒:序列与表观遗传学的结合
DOI:
10.1007/s11515-011-1118-6
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发表时间:
2011-04
期刊:
影响因子:
--
通讯作者:
Fangpu Han
中科院分区:
文献类型:
--
作者:
Wenchao Yin;James Birchler;Fangpu Han
The centromere is a highly organized structure mainly composed of repeat sequences, which make this region extremely difficult for sequencing and other analyses. It plays a conserved role in equal division of chromosomes into daughter cells in both mitosis and meiosis. However, centromere sequences show notable plasticity. In a dicentric chromosome, one of the centromeres can become inactivated with the underlying DNA unchanged. Furthermore, formerly inactive centromeres can regain activity under certain conditions. In addition, neocentromeres without centromeric repeats have been found in a wide spectrum of species. This evidence indicates that epigenetic mechanisms together with centromeric sequences are associated with centromere specification.
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DOI:
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期刊:
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