Transverse relaxation of saline and plasma using Mn(II), HSA–EDTA–Mn, and HSA–EDTA–Gd: Application to erythrocyte water exchange
Transverse relaxation of saline and plasma using Mn(II), HSA–EDTA–Mn, and HSA–EDTA–Gd: Application to erythrocyte water exchange
复制标题
使用 Mn(II)、HSA-EDTA-Mn 和 HSA-EDTA-Gd 进行盐水和血浆的横向弛豫:在红细胞水交换中的应用
DOI:
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发表时间:
1987
影响因子:
3.3
通讯作者:
J. Goldstein
中科院分区:
文献类型:
--
作者:
G. Caines;C. Morgan;R. C. Long;J. Goldstein
Enhancements of 1H nuclear magnetic transverse relaxation rates by Mn(II)‐ and Gd(III)‐ethylenediaminetetraacetic acid (EDTA)‐human serum albumin (HSA) complexes are compared with MnCl2 in human plasma and isotonic saline. HSA–EDTA–Mn and HSA–EDTA–Gd in saline, at physiological concentrations of HSA, afforded T2's comparable to 2 mM MnCl2 in 4% HSA saline. The above reagents are new and potentially useful relaxation agents for the measurement of H2O exchange rates in erythrocyte suspensions. The exchange rate of water across the red cell membrane was determined using these new reagents over the temperature range from 20 to 37°C. © 1987 Academic Press, Inc.
影响因子:
2.5
作者:
LAUFFER R B;BRADY T J
通讯作者:
BRADY T J