Infantile hydrocephalus: a review of epidemiology, classification and causes.
Infantile hydrocephalus: a review of epidemiology, classification and causes.
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DOI:
10.1016/j.ejmg.2014.06.002
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发表时间:
2014-08
影响因子:
1.9
通讯作者:
Dobyns WB
中科院分区:
文献类型:
--
作者:
Tully HM;Dobyns WB
Hydrocephalus is a common but complex condition caused by physical or functional obstruction of CSF flow that leads to progressive ventricular dilatation. Though hydrocephalus was recently estimated to affect 1.1 in 1,000 infants, there have been few systematic assessments of the causes of hydrocephalus in this age group, which makes it a challenging condition to approach as a scientist or as a clinician. Here, we review contemporary literature on the epidemiology, classification and pathogenesis of infantile hydrocephalus. We describe the major environmental and genetic causes of hydrocephalus, with the goal of providing a framework to assess infants with hydrocephalus and guide future research.
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