The Role of Context in Integrating Buprenorphine into a Drop-In Center in Kampala, Uganda, Using the Consolidated Framework for Implementation Research.

The Role of Context in Integrating Buprenorphine into a Drop-In Center in Kampala, Uganda, Using the Consolidated Framework for Implementation Research.
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DOI:
10.3390/ijerph191610382
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发表时间:
2022-08-20
影响因子:
--
通讯作者:
Musinguzi, Geofrey
Musinguzi, Geofrey
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Dickson-Gomez, Julia;Krechel, Sarah;Katende, Dan;Johnston, Bryan;Twaibu, Wamala;Glasman, Laura;Ogwal, Moses;Musinguzi, Geofrey

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背景:虽然非洲长期以来首当其冲地受到人体免疫机能丧失病毒(艾滋病毒)流行病的影响,但直到最近,该大陆一直被认为基本上没有非法药物使用,特别是没有注射药物使用。在乌干达,使用或注射毒品的人数(分别为PWUD和PWID)有所增加,PWID是感染人类免疫缺陷病毒(HIV)和丙型肝炎病毒(HCV)的高危关键人群。然而,包括提供清洁注射设备和药物辅助治疗在内的减少危害做法直到最近才在该国试行。该项目旨在将丁丙诺啡整合到减少危害的干预中心(DIC)。方法:采用《实施研究统一框架》指导我们将丁丙诺啡纳入降低危害DIC的现有实践。我们与社区咨询委员会成员和DIC工作人员进行了重要的信息提供者访谈,以记录这一过程,它的成功和失败。结果:结果表明,药物使用的刑事化和对PWUD的污名化挑战了在监管较少的社区环境中提供丁丙诺啡治疗的努力。结论:DIC工作人员及其对减少危害和宣传的承诺促进了获得必要批准的过程。
Background: Although Africa has long borne the brunt of the human immunodeficiency virus (HIV) epidemic, until recently, the continent has been considered largely free of illicit drug use and injection drug use in particular. In Uganda, the number of people who use or inject drugs (PWUD and PWID, respectively) has increased, and PWID are a key population at high risk for human immunodeficiency virus (HIV) and hepatitis C virus (HCV) infection. However, harm reduction practices, including providing clean injection equipment and medication-assisted treatment (MAT), have only recently been piloted in the country. This project aims to integrate buprenorphine into a harm reduction drop-in center (DIC). Methods: The Consolidated Framework for Implementation Research was used to guide our preparations to integrate buprenorphine into existing practices at a harm reduction DIC. We conducted key informant interviews with members of a community advisory board and DIC staff to document this process, its successes, and its failures. Results: Results indicate that criminalization of drug use and stigmatization of PWUD challenged efforts to provide buprenorphine treatment in less regulated community settings. Conclusions: DIC staff and their commitment to harm reduction and advocacy facilitated the process of obtaining necessary approvals.
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