A systematic review of patients' and providers' perspectives of medications for treatment of opioid use disorder.

A systematic review of patients' and providers' perspectives of medications for treatment of opioid use disorder.
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对患者和提供者对阿片类药物使用障碍的治疗药物的观点的系统评价。

DOI:
10.1016/j.jsat.2020.108146
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发表时间:
2020-12
影响因子:
3.9
通讯作者:
Springer SA
Springer SA
中科院分区:
医学2区
文献类型:
--
作者:
Cioe K;Biondi BE;Easly R;Simard A;Zheng X;Springer SA

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阿片类药物的流行是一场公共卫生危机。阿片类药物使用障碍(MOUD)的药物包括:1)丁丙诺啡,2)美沙酮,和3)缓释纳洛酮(XR-NTX)。研究应该调查患者和提供者对MOUD的看法,因为他们可以影响处方,保留和恢复。本系统综述主要关注患者和医疗服务提供者对MOUD的看法。审查合格性标准包括纳入关注的结局,英语,涉及≥ 18岁的患者。PubMed数据库检索得到1692个结果;我们在最终综述中纳入了152篇文章。有63篇关于丁丙诺啡的文章,115篇关于美沙酮的文章,16篇关于纳洛酮的文章。与MOUD相关的错误信息和耻辱是常见的患者主题。提供者报告说,缺乏培训和资源是MOUD的障碍。这篇综述表明,患者对MOUD有明显的错误信息。由于阿片类药物流行的严重性,研究必须考虑患者和提供者对OUD治疗的观点的影响,包括对处方MOUD类型,患者保留和依从性的影响,以及最终接受OUD治疗的患者数量,这将有助于遏制阿片类药物流行。
The opioid epidemic is a public health crisis. Medications for opioid use disorder (MOUD) include: 1) buprenorphine, 2) methadone, and 3) extended-release naltrexone (XR-NTX). Research should investigate patients’ and providers’ perspectives of MOUD since they can influence prescription, retention, and recovery. This systematic review focused on patients’ and providers’ perceptions of MOUD. The review eligibility criteria included inclusion of the outcome of interest, in English, and involving persons ≥ 18 years. A PubMed database search yielded 1692 results; we included 152 articles in the final review. There were 63 articles about buprenorphine, 115 articles about methadone, and 16 about naltrexone. Misinformation and stigma associated with MOUD were common patient themes. Providers reported lack of training and resources as barriers to MOUD. This review suggests that patients have significant misinformation regarding MOUD. Due to the severity of the opioid epidemic, research must consider the effects of patients’ and providers’ perspectives on treatment for OUD, including the effects on the type of MOUD prescribed, patient retention and adherence, and ultimately the number of patients treated for OUD, which will aid in curbing the opioid epidemic.
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