DNPTrapper: an assembly editing tool for finishing and analysis of complex repeat regions.

DNPTrapper: an assembly editing tool for finishing and analysis of complex repeat regions.
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DNPtrapper:用于复杂重复区域完成和分析的组装编辑工具。

DOI:
10.1186/1471-2105-7-155
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发表时间:
2006-03-20
期刊:
影响因子:
3
通讯作者:
Andersson, B
Andersson, B
中科院分区:
生物学4区
文献类型:
--
作者:
Arner, E;Tammi, MT;Tran, AN;Kindlund, E;Andersson, B

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Many genome projects are left unfinished due to complex, repeated regions. Finishing is the most time consuming step in sequencing and current finishing tools are not designed with particular attention to the repeat problem. We have developed DNPTrapper, a shotgun sequence finishing tool, specifically designed to address the problems posed by the presence of repeated regions in the target sequence. The program detects and visualizes single base differences between nearly identical repeat copies, and offers the overview and flexibility needed to rapidly resolve complex regions within a working session. The use of a database allows large amounts of data to be stored and handled, and allows viewing of mammalian size genomes. The program is available under an Open Source license. With DNPTrapper, it is possible to separate repeated regions that previously were considered impossible to resolve, and finishing tasks that previously took days or weeks can be resolved within hours or even minutes.
DOI: 10.1016/s0169-2607(01)00194-8
发表时间: 2003-01-01
影响因子: 6.1
作者:
Tammi, MT;Arner, E;Andersson, B
通讯作者: Andersson, B
DOI: 10.1172/jci104705
发表时间: 1963-01-01
影响因子: 15.9
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发表时间: 2004-03-22
期刊: BIOINFORMATICS
影响因子: 5.8
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DOI: 10.1093/bioinformatics/18.3.379
发表时间: 2002-03-01
期刊: BIOINFORMATICS
影响因子: 5.8
作者:
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通讯作者: Andersson, B
DOI: 10.1073/pnas.51.6.1291
发表时间: 1964-01-01
影响因子: 11.1
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通讯作者: SCHWEET, R