Association between Scale-Free Brain Dynamics and Behavioral Performance: Functional MRI Study in Resting State and Face Processing Task.
Association between Scale-Free Brain Dynamics and Behavioral Performance: Functional MRI Study in Resting State and Face Processing Task.
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DOI：
10.1155/2017/2824615
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发表时间：
2017
影响因子：
2.8
通讯作者：
Northoff G
中科院分区：
文献类型：
--
作者：
Kasagi M;Huang Z;Narita K;Shitara H;Motegi T;Suzuki Y;Fujihara K;Tanabe S;Kosaka H;Ujita K;Fukuda M;Northoff G
人类大脑活动的无标度动力学，其特征在于一个复杂的时间结构与无标度属性，可以量化使用幂律指数（PLE）作为一个指标。一般来说，幂律在自然界中是有据可查的，特别是在大脑中。一些先前的功能磁共振成像研究表明，较低的PLE在认知任务诱发的活动比在静息状态下的活动。然而，在认知任务诱发的活动及其与相关行为的关系PLE调制仍然不清楚。本研究在静息状态和面孔加工+控制任务中，分别研究了静息状态和任务诱发活动中的PLE，以及PLE与任务期间平均反应时（mRT）测量的行为之间的关系。我们发现：（1）面孔辨别引起内侧前额叶皮层（mPFC）、后扣带皮层（PCC）、杏仁核和梭状面孔区的BOLD信号变化;（2）任务诱发活动期间，特别是在mPFC中，与静息状态活动相比，PLE显著降低;（3）最重要的是，在mPFC中，mRT与静息状态PLE和静息-任务PLE差异显著负相关。这些结果可以导致更好地理解任务性能参数之间的关联（例如，mRT）和自发和任务诱发的脑活动的无标度动力学。
The scale-free dynamics of human brain activity, characterized by an elaborate temporal structure with scale-free properties, can be quantified using the power-law exponent (PLE) as an index. Power laws are well documented in nature in general, particularly in the brain. Some previous fMRI studies have demonstrated a lower PLE during cognitive-task-evoked activity than during resting state activity. However, PLE modulation during cognitive-task-evoked activity and its relationship with an associated behavior remain unclear. In this functional fMRI study in the resting state and face processing + control task, we investigated PLE during both the resting state and task-evoked activities, as well as its relationship with behavior measured using mean reaction time (mRT) during the task. We found that (1) face discrimination-induced BOLD signal changes in the medial prefrontal cortex (mPFC), posterior cingulate cortex (PCC), amygdala, and fusiform face area; (2) PLE significantly decreased during task-evoked activity specifically in mPFC compared with resting state activity; (3) most importantly, in mPFC, mRT significantly negatively correlated with both resting state PLE and the resting-task PLE difference. These results may lead to a better understanding of the associations between task performance parameters (e.g., mRT) and the scale-free dynamics of spontaneous and task-evoked brain activities.
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DOI：
10.1523/jneurosci.2041-09.2009
发表时间：
2009-10-28
期刊：
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子：
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作者：
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影响因子：
16.2
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影响因子：
5.7
作者：
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通讯作者：
Smith, S
影响因子：
3.7
作者：
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DOI：
10.1523/jneurosci.2111-11.2011
发表时间：
2011-09-28
期刊：
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子：
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作者：
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