Anti-NMDAR encephalitis in a 19 year old female patient with ovarian teratoma: A case report.
Anti-NMDAR encephalitis in a 19 year old female patient with ovarian teratoma: A case report.
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DOI：
10.1016/j.eurox.2021.100129
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发表时间：
2021-07
影响因子：
--
通讯作者：
Arsalane A
中科院分区：
文献类型：
--
作者：
El Hanna J;Quenum C;Arsalane A
抗N-甲基-d-天冬氨酸脑炎是自身免疫性脑炎的一个亚类。它以其侵略性的表现症状和快速恶化而闻名，但它对治疗有反应。50%与卵巢畸胎瘤有关.我们报告的情况下，一个19岁的女性病人提出的精神疾病的突然发作与迅速恶化。神经影像学检查支持脑炎，CSF检查显示抗NMDA受体。进一步的腹部成像显示右侧卵巢畸胎瘤4厘米。行腹腔镜卵巢囊肿切除术，给予皮质激素治疗、IVIG和抗惊厥药。我们报告7个月后症状完全消退。抗N-甲基-D-天冬氨酸受体脑炎合并卵巢畸胎瘤是一种罕见的快速恶化的疾病。早期诊断、手术切除和适当的药物治疗是治疗本病的关键。
Anti-N-Methyl-d-Aspartate encephalitis is a subcategory of auto-immune encephalitis. It is known for its aggressive presenting symptoms and rapid deterioration, yet it is treatment responsive. It is associated in 50 % to ovarian teratoma. We report the case of a 19 year old female patient presenting for a psychiatric disorder of sudden onset with rapid deterioration. Neurologic imaging was in favor of encephalitis, and CSF studies revealed Anti NMDA receptors. Further abdominal imaging showed a right ovarian teratoma of 4 cm. Laparoscopic ovarian cyst resection was done, and corticotherapy, IVIG and anticonvulsants were given. We report complete resolution of symptoms after 7 months. Anti-NMDA receptor encephalitis with ovarian teratoma is a rare entity with rapid deterioration. Early diagnosis, surgical resection and proper medical treatment are essential for the management of this disease.
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影响因子：
1.6
作者：
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通讯作者：
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