Periovulatory time courses of plasma estradiol and progesterone in the Japanese monkey (Macaca fuscata)
Periovulatory time courses of plasma estradiol and progesterone in the Japanese monkey (Macaca fuscata)
复制标题
日本猴（Macaca fuscata）血浆雌二醇和孕酮围排卵时程
作者：
H. Nigi;R. Torii
在20只日本猕猴的21个月经周期中测定了血浆雌二醇和孕酮的围排卵时间过程。两种类固醇激素均采用放射免疫法测定。通过对卵巢的连续腹腔镜观察来检测排卵。21个周期中有3个为无排卵周期。在其余18个排卵周期中，排卵前雌二醇峰值出现在月经周期的第12.2±1.4天（范围10-15）。峰值雌二醇浓度为431±199（范围210-930）pg/ml。雌激素峰值与排卵的时间间隔在48小时以内，最短为10-13小时，最长为32-48小时。在排卵后的前2天内，随着排卵后黄体的发育，孕酮的增加是非常缓慢的。18个排卵周期中有13个周期孕酮迅速升高，在排卵后4-8天达最高值，为4.0±1.2（2.3-5.7）ng/ml。在18个周期中的5个周期中，孕酮水平根本没有升高或不超过2.0 ng/ml，即使它们显示出或多或少的升高。5个周期的黄体期为8.2±1.6（6-10）d，较前13个周期的14.0±1.1（13-16）d明显缩短。
Periovulatory time courses of plasma estradiol and progesterone were determined in 21 menstrual cycles of 20 Japanese monkeys. Both steroids were measured by radioimmunoassay. Ovulation was detected by serial laparoscopic observations of the ovaries. Three of the 21 cycles were anovulatory cycles. In the remaining 18 ovulatory cycles, a preovulatory estradiol peak occurred on day 12.2±1.4 (range 10–15) of the menstrual cycle. The estradiol concentration at the peak was 431±199 (range 210–930) pg/ml. The time interval between the estradiol peak and ovulation was within 48 hr; the shortest interval was 10–13 hr and the longest 32–48 hr. Although the progesterone levels began to increase slightly (0.6–1.4 ng/ml) before ovulation, they did not show a continuous increase but decreased once before ovulation. The increase in progesterone with development of the corpus luteum after ovulation was very gradual during the first 2 days after ovulation. Subsequently, in 13 of 18 ovulatory cycles the progesterone levels rose rapidly and reached a maximum, 4.0±1.2 (range 2.3–5.7) ng/ml, 4–8 days after ovulation. In 5 of the 18 cycles, the progesterone levels did not rise at all or did not exceed 2.0 ng/ml even if they showed more or less an increase. In the 5 cycles, the length of the luteal phase was 8.2±1.6 (range 6–10) days, which was significantly shorter than that of the former 13 cycles with 14.0±1.1 (range 13–16) days.
阿萨姆猴（Macaca assamensis）月经周期的内分泌特征。
影响因子：
3.6
作者：
Wehrenberg,WB;Dyrenfurth,I;Ferin,M
通讯作者：
Ferin,M