Puberty and perimenopause: reproductive transitions and their implications for women's health.

Puberty and perimenopause: reproductive transitions and their implications for women's health.
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DOI:
10.1016/j.socscimed.2015.03.031
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发表时间:
2015-05
影响因子:
5.4
通讯作者:
Falconi, April M.
Falconi, April M.
中科院分区:
医学2区
文献类型:
--
作者:
Hoyt, Lindsay Till;Falconi, April M.

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这一范围审查综合了现有的研究两个主要的过渡,在女性的生活:青春期和围绝经期。这两个巨大的生理变化时期划分了生殖生命周期的开始和结束,并与两个关键系统的主要神经内分泌重组有关,下丘脑-垂体-性腺(HPG)轴和下丘脑-垂体-肾上腺(HPA)轴。尽管越来越多的证据表明青春期和围绝经期的时间和经历与各种身心健康结果有关(例如,情绪障碍、新陈代谢、心血管健康、自身免疫性疾病和癌症),这两个过程很少一起检查。在本文中,我们桥接这些不同的文献,突出相似之处,隔离不一致,并确定未来研究的重要领域,在妇女的健康。
This scoping review synthesizes existing research on two major transitions in females’ lives: puberty and perimenopause. These two periods of vast physiological change demarcate the beginning and the end of the reproductive life cycle and are associated with major neuroendocrine reorganization across two key systems, the hypothalamic-pituitary-gonadal (HPG) axis the hypothalamus-pituitary-adrenal (HPA) axis. Despite growing evidence suggesting that the timing and experience of puberty and perimenopause are related to various physical and mental health outcomes (e.g., mood disorders, metabolism, cardiovascular health, autoimmune conditions and cancer), these two processes are rarely examined together. In this paper, we bridge these disparate literatures to highlight similarities, isolate inconsistencies, and identify important areas for future research in women’s health.
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