The expanding family of neutrophil-derived extracellular vesicles.
The expanding family of neutrophil-derived extracellular vesicles.
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DOI：
10.1111/imr.13103
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发表时间：
2022-11
影响因子：
8.7
通讯作者：
中科院分区：
文献类型：
--
作者：
中性粒细胞是参与几种炎症和稳态过程的免疫细胞。它们释放货物的能力可以根据货物是单独释放还是与质膜结构结合释放来分类。无质膜分泌模式的实例是脱粒、中性粒细胞胞外陷阱（NET）释放和通过炎性小体形成的细胞因子释放。研究最多的膜覆盖的嗜中性粒细胞衍生的结构是外泌体和外体，统称为细胞外囊泡（EV）。凋亡囊泡是另一种公认的EV亚型。在过去的十年中，额外的膜覆盖的嗜中性粒细胞衍生的结构进行了表征：迁移的胞质，migrasomes，和细长的嗜中性粒细胞衍生的结构（ENDS）。所有这些结构都比中性粒细胞小，不能自我复制，因此符合EV的最新共识定义。在这篇综述中，我们专注于研究较少的中性粒细胞EV：凋亡囊泡，细胞质，migrasomes，和ENDS。
Neutrophils are immune cells involved in several inflammatory and homeostatic processes. Their capacity to release cargo can be classified based on whether the cargo is released on its own, or in conjunction with plasma membrane structures. Examples of plasma membrane-free secretion modes are degranulation, neutrophil extracellular trap (NET) release, and cytokine release through inflammasome formation. The most studied membrane-covered neutrophil-derived structures are exosomes and ectosomes that are collectively called extracellular vesicles (EV). Apoptotic vesicles are another recognized EV subtype. Over the last decade, additional membrane-covered neutrophil-derived structures were characterized: migratory cytoplasts, migrasomes, and elongated neutrophil-derived structures (ENDS). All these structures are smaller than the neutrophils, cannot reproduce themselves, and thus meet the latest consensus definition of EVs. In this review, we focus on the less well-studied neutrophil EVs: apoptotic vesicles, cytoplasts, migrasomes, and ENDS.
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影响因子：
4.7
作者：
Botha J;Pugsley HR;Handberg A
通讯作者：
Handberg A
DOI：
10.1016/bs.abl.2020.09.003
发表时间：
2020-01-01
期刊：
ADVANCES IN BIOMEMBRANES AND LIPID SELF-ASSEMBLY, VOL. 32
影响因子：
--
作者：
Bozic, Darja;Hocevar, Matej;Kralj-Iglic, Veronika
通讯作者：
Kralj-Iglic, Veronika
影响因子：
64.5
作者：
Genschmer, Kristopher R.;Russell, Derek W.;Blalock, J. Edwin
通讯作者：
Blalock, J. Edwin
影响因子：
32.4
作者：
Adrover, Jose M.;del Fresno, Carlos;Hidalgo, Andres
通讯作者：
Hidalgo, Andres
影响因子：
4.6
作者：
Headland SE;Jones HR;D'Sa AS;Perretti M;Norling LV
通讯作者：
Norling LV